Results 201 to 210 of about 3,121,398 (313)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Ethical Guidance for Investigational Implantable Neural Device Studies: Recommendations for Researchers and Research Ethics Committees. [PDF]

Neuromodulation
van Stuijvenberg OC, Bassil KC, de Vos CC, Geleijnse G, Noordmans HJ, Broekman MLD, van der Graaf R, Bertens RM, Lázaro-Muñoz G, Jongsma KR.   +9 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Strengthening Research Ethics Capacity in West Africa, 2015-2024. [PDF]

J Empir Res Hum Res Ethics
Ferguson K, Adebamowo C, Adejumo AO, Ogundiran T, Aliyu MH, Gordon EJ, Iliyasu Z, Agulanna C, Adamu SU, Adeyemo O, Ezugwu EC, Adeyemo SA, Caplan AL, Ogedegbe O, Moon TD, Heitman E, Taylor JC, Bari I, Hyder AA, Ndebele P, Doumbia S, Njie-Carr VPS, Sey-Sawo J, Silverman H, Usuf E, Senghore T, de Pina Araújo IIM, Laar AK, Ezeome ER.   +28 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

මාර්ගගත ක්‍රමවල සුරක්ෂිතභාවය පිළිබඳ පනත් කෙටුම්පත පාර්ලිමේන්තුවේදී සම්මත වීම සිංහල සහ ඉංග්‍රීසි පුවත්පත් මුල්පිටු සිරස්තල දැක්වූ ආකාරය

This entry includes a write-up and an infographic (both in Sinhala).On January 25, 2024, Ethics Eye posted a post showing the front page headlines from Sinhala and English newspapers about the passing of the Online Safety Bill.
Ethics Eye
core  

"Who are you going to call?:" Research ethics consultation directors' perspectives on barriers and facilitators. [PDF]

J Clin Transl Sci
Miner SA, McCormick JB, Taylor HA.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Development, validation and psychometric evaluation of the Plagiarism and Research Ethics Questionnaire (PRE-Q) among pharmacy students in Karachi, Pakistan. [PDF]

Sci Rep
Shakeel S, Ishaq H, Maqbool T, Rehman H, Ali M, Ishaqui AA, Aziz S, Sadia H, Naveed S, Azhar S, Jamshed S.   +10 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source