Results 91 to 100 of about 66,392,740 (260)

Ethics Committees in Ayurvedic PG institutions: Losing opportunities of making an impact

Journal of Ayurveda and Integrative Medicine, 2018
Ethics is a crucial component of medical practice world over and also an indispensable part of medical research. Ethics in medical practice primarily refers to not harming the patients by the proposed interventions; similarly ethics in research refers to
Sanjeev Rastogi
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A Clash of Paradigms? Ethnography and Ethics Approval

SAGE Open, 2017
Obtaining ethics approval from university ethics committees is an important part of the research process in Australia and internationally. However, for researchers engaging in ethnographic work, obtaining ethics approval can (re)present significant ...
Virginia Mapedzahama, Tinashe Dune
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Submission to Healthcare Ethics Committees in Portugal: Our Experience

Acta Médica Portuguesa
N/a.
Daniela Ribeiro, Carolina Sotana, Goranka Petriček, Joana Azeredo, Bruno Heleno   +4 more
doaj   +1 more source

Measuring inconsistency in research ethics committee review

BMC Medical Ethics, 2017
Background The review of human participant research by Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) is a complex multi-faceted process that cannot be reduced to an algorithm. However, this does not give RECs/ IRBs permission to
Samantha Trace, Simon Erik Kolstoe
doaj   +1 more source

Local Research Ethics Committees Can Audit Ethical Standards in Research

, 1997
OBJECTIVES: To show that a Local Research Ethics Committee (LREC) can carry out an audit of ethical standards in research. To find out if a researcher met certain ethical standards in recruiting subjects for clinical trials and in obtaining their consent.
Berry, Jonathan
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Challenges in the ethics review process of clinical scientific research projects in China

Journal of International Medical Research, 2019
Purpose Ethics review processes have become increasingly complex. The objective of this study was to explore the challenges currently faced in ethics reviews of clinical scientific research projects in China, with the goal of standardizing the structure ...
Zhu-Heng Wang, Guan-Hua Zhou, Li-Ping Sun, Jun Gang   +3 more
doaj   +1 more source

Two Models of Ethics Committees

, 2005
A distinction is made between two models of ethics committees. According to the Mirror Model, ethics committees ought to reflect the values of society.
Clarke, Simon
core   +1 more source