Results 81 to 90 of about 66,392,740 (260)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Assessing Perceptions of Research Ethics in Higher Education Institutions in Khyber Pakhtunkhwa-Pakistan

Bioscientific Review
Background. The current study aimed to assess the level of perceptions, attitudes, and awareness regarding research ethics among faculty members and postgraduate students in Higher Education Institutions (HEIs) of Khyber Pakhtunkhwa (KPK), Pakistan ...
Muhammad Ilyas, Shehryar Ahmad, Atta ur Rehman, Muhammad Ayaz, Raza Ullah, Sheraz Ahmad, Muhammad Haroon   +6 more
doaj   +1 more source

Business Ethics in Ethics Committees?

, 1990
The "Ethics committees" column in this issue of ...
Boyle, Philip
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Conhecimento e envolvimento de graduandos em fisioterapia acerca dos preceitos éticos da experimentação animal

Revista Bioética
O artigo analisa em amostra de universitários do curso de fisioterapia indicadores éticos ao uso de animais na pesquisa e no ensino e o nível de conhecimento e interesse dos alunos sobre o tema ética animal.
Igor Fagioli Bordello Masson, Cristiano Schiavinato Baldan, Vanessa Reimberg Ramalho, Ivaldo Esteves Junior, Daniela Fagioli Masson, Beatriz de Oliveira Peixoto, Cassio Marcos Vilicev, Thiago Saikali Farcic   +7 more
doaj  

Research ethical committees and ethics dumping

Current Medicine Research and Practice, 2022
N A Uvais
doaj   +1 more source

Differences and structural weaknesses of institutional mechanisms for health research ethics: Burkina Faso, Palestine, Peru, and Democratic Republic of the Congo

BMC Medical Ethics, 2018
Background Regardless of national contexts, the institutions responsible for research ethics, founded on international regulations, are all expected to be structured and to operate in a common way.
N’koué Emmanuel Sambiéni
doaj   +1 more source

Research, Ethics Committees and Legal Issues

, 2003
Who should be publicly authorized to consider legal issues in research? This paper argues that public policy should authorise ethics committees to consider legal issues about their own actions regarding particular research proposals; and that it should ...
Moore, Andrew
core  

Clinical ethics committees : a worldwide development

, 2001
Clinical ethics committees (CECs) are well established in North America where they are known as hospital or health care ethics committees. Similar groups and other kinds of clinical ethics support are now developing in Europe.
Ashcroft, Richard, Slowther, Anne, Hope, Tony   +2 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source