Results 141 to 150 of about 841,358 (341)
Yixue yu zhexueIn order to further standardize the management of investigator-initiated trial (IIT) in medical and healthcare institutions, the Administrative Measures for Conducting Investigator-Initiated Trial in Medical and Healthcare Institutions officially came ...
Zhe LIN, Ping REN, Ce ZHANG, Jiyin ZHOU
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
THE ROLE OF GOOD PRACTICES IN THE MANAGEMENT OF ETHICAL PROGRAMS IN HOSPITAL ESTABLISHMENTS. A FURTHER STEP FROM ETHICS COMMITTEES [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2012 This article is a review of both the functions and roles played by ethics committees in hospital establishments,and respectively of the challenges they are confronted with, in the general context of activities concerned withorganizational ethics ...
AGHEORGHIESEI (CORODEANU) DANIELA-TATIANA
doaj
The ESRC's 2010 Framework for Research Ethics: Fit for Research Purpose? [PDF]
The ESRC\'s (2010) Framework for Research Ethics extends the remit of its 2005 research ethics framework in three significant ways: the system is to be fully mandatory and it will no longer possible to make the case that no out of the ordinary ethical ...
Liz Stanley, Sue Wise
core
Barriers and enablers to optimal consumer involvement in research: the perspectives of health and medical researchers in the UK [PDF]
, 2011 Numerous reasons exist for involving consumers in research, falling mainly into three categories: moral/ethical, methodological, and political. The moral and ethical reasons for involving consumers in research centre on concepts of rights, citizenship ...
Ward, Paul Russell
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Strengthening postapproval oversight in research ethics committees: Challenges and solutions. [PDF]
Perspect Clin Res, 2023 Shetty YC, Seetharaman R.
europepmc +1 more source