Results 141 to 150 of about 194,883 (245)

Evaluation of Activities and Operations of Institutional Health Research Ethics Committees in Southeast Nigeria. [PDF]

J Empir Res Hum Res Ethics
Ityough JV, Aniwada EA, Ezeome ER.
europepmc   +1 more source

A longitudinal assessment of trial protocols approved by research ethics committees: The Adherance to SPIrit REcommendations in the UK (ASPIRE-UK) study. [PDF]

Trials, 2022
Speich B, Odutayo A, Peckham N, Ooms A, Stokes JR, Saccilotto R, Gryaznov D, von Niederhäusern B, Copsey B, Altman DG, Briel M, Hopewell S.   +11 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Scientific integrity from a meta-ethical perspective: more contextualization and research ethics committees? A preliminary meta-ethics study. [PDF]

BMC Res Notes
Stoeklé HC, Lasterie R, Hervé C.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Perspectives of Research Ethics Committees on the Challenges of Human Genomic Research Participation in Ethiopia. [PDF]

J Empir Res Hum Res Ethics
Dembu HS, Getachew H, Price PJ, Sales J, Wassie L.   +4 more
europepmc   +1 more source

Ethical concerns in suicide research: thematic analysis of the views of human research ethics committees in Australia. [PDF]

BMC Med Ethics, 2021
Barnard E, Dempster G, Krysinska K, Reifels L, Robinson J, Pirkis J, Andriessen K.   +6 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Strengthening ethics review of the development of artificial intelligence (AI) systems in health research: a guide for research ethics committees in Uganda. [PDF]

BMC Med Ethics
Nabukenya S, Wasswa W, Twimukye A, Mwaka ES.   +3 more
europepmc   +1 more source

Rethinking the role of Research Ethics Committees in the light of Regulation (EU) No 536/2014 on clinical trials and the COVID-19 pandemic. [PDF]

Br J Clin Pharmacol, 2022
Tusino S, Furfaro M.
europepmc   +1 more source