Results 171 to 180 of about 57,215,976 (259)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Evaluation of the Indian Health Service Adolescent Regional Treatment Centers

, 2014
This study evaluated the effectiveness and efficiency of, and consumer satisfaction with, the nine regional treatment centers (RTC's) that provide alcoholism and substance abuse rehabilitation treatment to American Indian and Alaska Native youth.
Support Services, Inc., Silver Spring, MD.
core  

Knowledge Production and Transfer in the Iranian Oral Health Research Centers: Based on Research Evaluation from 2019 to 2021. [PDF]

Front Dent
Falahat K, Baradaran Eftekhari M, Ramezani A.   +2 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

COVID-19 advocacy bias in the <i>BMJ</i>: meta-research evaluation. [PDF]

BMJ Open Qual
Kepp KP, Cristea I, Muka T, Ioannidis JPA.   +3 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Toward standardized methods in canine vaginal microbiome research: evaluation of storage, host DNA depletion, and database selection. [PDF]

Microbiol Spectr
Spanoghe L, Domain G, Posastiuc F, Hettiarachchi A, Panattoni A, Theuns S, Van Immerseel F, Opsomer G, Van Soom A, Banchi P.   +9 more
europepmc   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Japanese medical researchers' perceptions of quantitative research evaluation metrics and their psychological well-being: a cross-sectional study. [PDF]

Environ Health Prev Med
Minoura A, Kuwahara K, Shimada Y, Fukushima H, Kondo M, Sugiyama T.   +5 more
europepmc   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source