Results 151 to 160 of about 57,215,976 (259)

Responsible research evaluation: integrating quality, leadership, and integrity in national systems. The case of Peru. [PDF]

Front Res Metr Anal
Millones-Gómez PA, Castillo-Nunez JPS, Paucca-Calla KJ, Minchón-Medina CA, Castro-Delgado VL, Sotelo-Llancari S, Ignacio-Punin C, Rodríguez-Salazar DY, Urrutia-Baca VH.   +8 more
europepmc   +1 more source

Application of a feature extraction and normalization method to improve research evaluation across clinical disciplines. [PDF]

Ann Transl Med, 2021
Liu R, Liu Q, Shi J, Yu W, Gong X, Chen N, Yang Y, Huang J, Wang Z.   +8 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Evaluation of Scaling Efforts in CGIAR: Technical Note

CGIAR has maintained a long-standing commitment to scaling the public benefits of its innovations and has recently reinforced this priority. This renewed emphasis has generated an increasing need for the systematic evaluation of scaling efforts.
CGIAR Independent Advisory and Evaluation Service
core  

Beyond cumulative impact: the he-index and a volume-normalized efficiency metric for research evaluation. [PDF]

Front Res Metr Anal
Laimon M.
europepmc   +1 more source

Insights from the evaluations of the NIH Centers for Accelerated Innovation and Research Evaluation and Commercialization Hubs programs. [PDF]

J Clin Transl Sci, 2022
Anderson BJ, Leonchuk O, O'Connor AC, Shaw BK, Walsh AC.   +4 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Generative AI can and should accelerate research evaluation reform to better recognize 'distinctly human contributions'. [PDF]

Res Eval
Hosseini M, Earp BD, Porsdam Mann S, Holmes K.   +3 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Streamlining Trauma Research Evaluation With Advanced Measurement (STREAM) Study: Implementation of the PROMIS Toolbox Within an Orthopaedic Trauma Clinical Trials Consortium. [PDF]

J Orthop Trauma, 2022
Carlini AR, Collins SC, Staguhn ED, Frey KP, O'Toole RV, Archer KR, Obremskey WT, Agel J, Kleweno CP, Morshed S, Weaver MJ, Higgins TF, Bosse MJ, Levy JF, Wu AW, Castillo RC, METRC.   +16 more
europepmc   +1 more source