Results 131 to 140 of about 57,215,976 (259)

Working together to strengthen skills : IDRC's strategic evaluation of capacity development, phase 3; developing the framework

open access: yes, 2007
French version available in IDRC Digital Library: Renforcement concerté des capacités : phase 3 de l'évaluation stratégique des activités de renforcement des capacités du CRDI; élaboration du cadre d'évaluationThis “Evaluation Highlights ...
IDRC. Evaluation Unit
core  

Early Engagement in HIV Research: Evaluation of the Penn CFAR Scholars Program Aimed at Increasing Diversity of the HIV/AIDS Workforce. [PDF]

open access: yesJ Acquir Immune Defic Syndr, 2023
Kreider EF   +12 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Wheat Seed and Agricultural Programming in Afghanistan: Its Potential to Impact on Livelihoods

open access: yes, 2004
This report outlines the results of one of three combined “special studies,” conducted under the auspices of the European Commission-funded Afghanistan Research and Evaluation Unit (AREU) livelihoods monitoring research project.
Coke, Alexia   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A Logic Model Framework for Planning an International Refugee Health Research, Evaluation, and Ethics Committee. [PDF]

open access: yesHealth Promot Pract, 2022
Payton C   +5 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Peer Review Research Evaluation in Iran: Strengths, Weaknesses and Suggestions. [PDF]

open access: yesIran J Public Health, 2021
Eftekhari MB   +3 more
europepmc   +1 more source

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