Results 131 to 140 of about 4,970,902 (314)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 2014 As part of the US government’s Feed the Future initiative that aims to address global hunger and food security issues in sub-Saharan Africa, the US Agency for International Development is supporting multi-stakeholder agricultural research projects under ...
International Food Policy Research Institute (IFPRI)
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Two Decades of Political Science Research Assessment
Italian Political Science, 2018 Today, there is a general acceptance of, or at least resignation about, Dutch Research Assessments, whether in political science or in other disciplines. Research assessment exercises started in the Netherlands in 1993, and are held every six years. To a
Rudy B. Andeweg
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
China's Research Evaluation Reform: What are the Consequences for Global Science? [PDF]
Minerva, 2022 Shu F, Liu S, Larivière V.
europepmc +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
SociologicaThe rise of quantitative research evaluation has changed not only the way knowledge is rated and ranked, but the way scientific knowledge is produced. This Focus discusses the outcomes of Juan Pablo Pardo-Guerra’s research on the transformation of the ...
Riccardo Emilio Chesta
doaj +1 more source
The Thoracic Research Evaluation and Treatment 2.0 Model: A Lung Cancer Prediction Model for Indeterminate Nodules Referred for Specialist Evaluation. [PDF]
Chest, 2023 Godfrey CM +17 more
europepmc +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source