Results 141 to 150 of about 57,215,976 (259)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Editorial: Linked open bibliographic data for real-time research assessment

open access: yesFrontiers in Research Metrics and Analytics, 2023
Mohamed Ben Aouicha   +2 more
doaj   +1 more source

Defining Rurality in Hospice Research: Evaluation of Common Measures. [PDF]

open access: yesJ Health Care Poor Underserved, 2021
Svynarenko R, Lindley LC.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Programme Partnership Arrangement Evaluation 2014: A primary research feedback report

open access: yes, 2015
The UK's Department for International Development (DFID) is one of Oxfam's most strategically important partners. The Programme Partnership Arrangement (PPA) is a major element of Oxfam's relationship with DFID, providing valuable opportunities for ...

core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Influence of Orthopedic Journals in Knee Arthritis Treatment Research: Evaluation Using Relative Citation Ratio. [PDF]

open access: yesCureus, 2022
Megalla M   +7 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Distinct domains: a call for nuance in the categorization and evaluation of “Arts and Humanities” disciplines

open access: yesFrontiers in Research Metrics and Analytics
William E. Savage   +2 more
doaj   +1 more source

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