Results 41 to 50 of about 284,249 (298)
The Moving Hotspots model for kHz QPOs in accreting neutron stars
3D MHD simulation of accretion onto neutron stars have shown in the last few years that the footprint (hotspot) of the accretion flow changes with time.
Bachetti, Matteo, Romanova, Marina
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Background Osteonecrosis of the femoral head (ONFH) is a progressive, debilitating orthopedic condition that primarily results from compromised vascular supply.
Kai Pang +5 more
doaj +1 more source
Relativistic and slowing down: the flow in the hotspots of powerful radio galaxies and quasars [PDF]
Pairs of radio emitting jets with lengths up to several hundred kiloparsecs emanate from the central region (the `core') of radio loud active galaxies.
Demosthenes Kazanas +5 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Bibliometric Analysis of the Outdoor Thermal Environment Based on CiteSpace
The outdoor thermal environment (OTE) is closely related to sustainable urban development and human living, and related research has attracted widespread attention.
Chao Xie, Tangjun Feng, Li Hu
doaj +1 more source
On the Prospect of Constraining Black-Hole Spin Through X-ray Spectroscopy of Hotspots [PDF]
Future X-ray instrumentation is expected to allow us to significantly improve the constraints derivedfrom the Fe K lines in AGN, such as the black-hole angular momentum (spin) and the inclination angle of the putative accretion disk.
Blandford +23 more
core +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Background The recent surge in clinical and nonclinical health-related data has been accompanied by a concomitant increase in personal health data (PHD) research across multiple disciplines such as medicine, computer science, and management.
Jianxia Gong +3 more
openaire +3 more sources

