Results 51 to 60 of about 123,677 (311)

The bibliometric and visualization analysis of alcohol-induced osteonecrosis of the femoral head: research trends and future directions (1998–2024)

Journal of Orthopaedic Surgery and Research
Background Osteonecrosis of the femoral head (ONFH) is a progressive, debilitating orthopedic condition that primarily results from compromised vascular supply.
Kai Pang, Huiying Li, Haifeng Chen, Zhentao Man, Dandan Wang, Wei Li   +5 more
doaj   +1 more source

Research Hotspots and Trends of Deep Learning in Critical Care Medicine: A Bibliometric and Visualized Study

, 2023
Kaichen Zhang,* Yihua Fan,* Kunlan Long, Ying Lan, Peiyang Gao Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Peiyang Gao ...
Gao P, Zhang K, Fan Y, Long K, Lan Y
core  

Hitting hotspots: spatial targeting of malaria for control and elimination. [PDF]

, 2012
Teun Bousema and colleagues argue that targeting malaria “hotspots” is a highly efficient way to reduce malaria transmission at all levels of transmission ...
Sauerwein, Robert W, Bousema, Teun, David L Smith, Smith, David L, Sauerwein, R.W., Gosling Roly, Churcher, Thomas S, Drakeley, Chris, Gosling, R., Griffin Jamie T., Teun Bousema, Chris Drakeley, Thomas S Churcher, Takken, W., Azra Ghani, Griffin, J.T., Bousema, T., Churcher, T.S., Smith, D.L., Griffin, Jamie T, Takken, Willem, Takken Willem, Drakeley Chris, Ghani, Azra, Bousema Teun, Jamie T Griffin, Churcher Thomas S., Sauerwein Robert W., Gosling, Roly, Drakeley, C., Ghani Azra, Robert W Sauerwein, Smith David L., Ghani, A., Willem Takken, Roly Gosling   +35 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A Bibliometric Analysis of the Outdoor Thermal Environment Based on CiteSpace

Buildings
The outdoor thermal environment (OTE) is closely related to sustainable urban development and human living, and related research has attracted widespread attention.
Chao Xie, Tangjun Feng, Li Hu
doaj   +1 more source

Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam, Tanzania [PDF]

, 2016
BACKGROUND: Malaria transmission, primarily mediated by Anopheles gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding.
Mwakalinga, Victoria M., Mageni, Zawadi D, Mlacha, Yeromin P., Paliga, John M, Coetzee, Maureen, Sartorius, Benn K D, Mwakalinga, Victoria M, Killeen, Gerry F., Killeen, Gerry, Dongus, Stefan, Govella, Nicodem J, Sartorius, Benn K. D., Killeen, Gerry F, Mlacha, Yeromin P, Msellemu, Daniel F, Mageni, Zawadi D., Paliga, John M., Govella, Nicodem J., Limwagu, Alex J., Msellemu, Daniel F., Limwagu, Alex J   +20 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Land Use Carbon Emissions or Sink: Research Characteristics, Hotspots and Future Perspectives [PDF]

The land use, land-use change and forestry (LULUCF) sector, as a source and a sink of greenhouse gas (GHG) emissions, is critical for achieving carbon neutrality.
Shaojian Wang, Maraseni, Tek Narayan, Lina Liu, Rong Wu, Wang, Shaojian, Jiansheng Qu, Suman Aryal, Zhang, Zhenhua, Wu, Rong, Qu, Jiansheng, Feng Gao, Aryal, Suman, Gao, Feng, Liu, Lina, Zhenhua Zhang, Tek Narayan Maraseni   +15 more
core   +1 more source

Congruence between global crop wild relative hotspots and biodiversity hotspots [PDF]

, 2022
Biodiversity is currently experiencing exceptional loss due to the activities of humans, negatively impacting the ecosystem services on which humanity relies.
Maxted, Nigel, Hole, David, Vincent, Holly   +2 more
core   +1 more source