Results 61 to 70 of about 123,677 (311)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Mapping the evolving trend of research on efferocytosis: a comprehensive data-mining-based study

BioData Mining
Background Efferocytosis, the process by which apoptotic cells are recognized and removed by phagocytes, plays a critical role in maintaining tissue homeostasis and modulating inflammatory responses.
Yanpeng Jian, Shijia Dong, Weijie Liu, Genfeng Li, Xiaoyu Lian, Yigong Wang   +5 more
doaj   +1 more source

Ten global "hotspots" for the neglected tropical diseases.

, 2014
In this article, Peter Hotez, fellow in disease and poverty, summarizes 10 of the worst global ﾓhotspotsﾔ where neglected tropical diseases ...
Hotez, Peter J., Peter J Hotez
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Research hotspots and trends of plumbagin: A bibliometric perspective

Medicine
Plumbagin is a biologically active naphthoquinone compound. Research related to plumbagin has gained popularity, evidenced by a gradual increase in publications. However, a bibliometric study in this field has yet to be conducted. Consequently, this study aims to evaluate the global scientific output of plumbagin research through bibliometric analysis,
Zichen Xu, Yuqi Xin, Xinjian Zhang, Jianwei Liu, Yang Liu, Runying Guo, Qingkun Jiang, Jiaxuan Qiu   +7 more
openaire   +2 more sources

Prebiotics, Probiotics, and Synbiotics—A Research Hotspot for Pediatric Obesity

Microorganisms, 2023
Childhood obesity is a major public health problem worldwide with an increasing prevalence, associated not only with metabolic syndrome, insulin resistance, hypertension, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD), but also with psychosocial problems.
Reka Borka Balas, Lorena Elena Meliț, Ancuța Lupu, Vasile Valeriu Lupu, Cristina Oana Mărginean   +4 more
openaire   +3 more sources

Final countdown for biodiversity hotspots

, 2019
Most of Earth's biodiversity is found in 36 biodiversity hotspots, yet less than 10% natural intact vegetation remains. We calculated models projecting the future state of most of these hotspots for the year 2050, based on future climatic and ...
Habel, Jan C., Livia Rasche, Engler, Jan Oliver, Lens, Luc, Hilde Eggermont, Jan O. Engler, Meyer, Sebastian T, Luc Lens, Roedder, Dennis, del Diego, Ruth Sos, Schneider, Uwe A, Schneider, Uwe A., Sos del Diego, Ruth, Stork, Nigel E., Dennis Rödder, Natalie Trapp, Erwin Schmid, Nigel E. Stork, Rasche, Livia, Eggermont, Hilde, Jan C. Habel, Engler, Jan O, Uwe A. Schneider, Sebastian T. Meyer, Habell, Jan C, Trapp, Natalie, Stork, Nigel E, Rödder, Dennis, Schmid, Erwin, Ruth Sos del Diego, Meyer, Sebastian T.   +30 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Visualization Analysis of Subsurface Drip Irrigation Research Based on CiteSpace

Guan'gai paishui xuebao, 2023
【Objective】 The development and application of subsurface drip irrigation is of great importance for helping mitigate the limitation of water resources faced by agriculture in arid and semiarid regions around the world.
WEI Qi, HE Min, WEI Qi, XU Junzeng, LI Xintong, DONG Yixiao, LI Yan   +6 more
doaj   +1 more source

UBI-hotspots

, 2010
We report a novel deployment of so-called UBI-hotspots in a city center to establish an ecosystem infrastructure for conducting diverse urban computing research and business in authentic urban setting.
T. Lindén, Kukka, H., Ojala, T., Heikkinen, T., Hosio, S., S. Hosio, M. Jurmu, Lindén, T., T. Ojala, F. Kruger, T. Heikkinen, H. Kukka, Valkama, V., V. Valkama, Jurmu, Marko; id_orcid, Kruger, F.   +15 more
core   +1 more source