Results 71 to 80 of about 71,099,589 (355)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mapping the evolving trend of research on efferocytosis: a comprehensive data-mining-based study

BioData Mining
Background Efferocytosis, the process by which apoptotic cells are recognized and removed by phagocytes, plays a critical role in maintaining tissue homeostasis and modulating inflammatory responses.
Yanpeng Jian, Shijia Dong, Weijie Liu, Genfeng Li, Xiaoyu Lian, Yigong Wang   +5 more
doaj   +1 more source

Ozone therapy for knee osteoarthritis: a literature visualization analysis of research hotspots and prospects

Medical Gas Research
Medical ozone is a molecule composed of three oxygen atoms with anti-inflammatory, analgesic, and antioxidant functions. Ozone therapy (O3 or O2– O3) for knee osteoarthritis has gradually received increasing attention from researchers in recent years ...
Qing Liu, Jian Liu, Guang-Lei Cao, Yuan Liu, Ye Huang, Xie-Yuan Jiang   +5 more
semanticscholar   +1 more source

Epidemiology of Subpatent Plasmodium Falciparum Infection: Implications for Detection of Hotspots with Imperfect Diagnostics. [PDF]

, 2013
At the local level, malaria transmission clusters in hotspots, which may be a group of households that experience higher than average exposure to infectious mosquitoes.
Bousema, T., Bousema, Teun, Atwal, S., Kibiki, Gibson, Greenhouse, Bryan, Gadalla, Nahla, Sturrock, Hugh Jw, Sutherland, Colin J, Chandramohan, Daniel, Mosha, Jacklin F, Greenwood, B.M., Drakeley, Chris, Gosling, R., Kibiki, G.S., Gosling, Roly, Drakeley, C., Gadalla, N., Sturrock, H.J., Greenhouse, B., Mosha, J.F., Sutherland, C.J., Greenwood, Brian, Atwal, Sharan, Chandramohan, D.   +23 more
core   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Visualization Analysis of Subsurface Drip Irrigation Research Based on CiteSpace

Guan'gai paishui xuebao, 2023
【Objective】 The development and application of subsurface drip irrigation is of great importance for helping mitigate the limitation of water resources faced by agriculture in arid and semiarid regions around the world.
WEI Qi, HE Min, WEI Qi, XU Junzeng, LI Xintong, DONG Yixiao, LI Yan   +6 more
doaj   +1 more source

A data-driven analysis to discover research hotspots and trends of technologies for PFAS removal.

Environmental Research
The frequent detection of persistent per- and polyfluoroalkyl substances (PFAS) in organisms and environment coupled with surging evidence for potential detrimental impacts, have attracted widespread attention throughout the world.
Xiaoya Fang, Li-Li Jin, Xiang-wu Sun, Hui Huang, Yan-Ru Wang, Hong-Qiang Ren   +5 more
semanticscholar   +1 more source

Research Hotspots and Evolution Trends of Carbon Neutrality—Visual Analysis of Bibliometrics Based on CiteSpace

Sustainability, 2022
Climate change is one of the most urgent challenges facing the world. All countries should take joint actions to achieve the goal of carbon neutrality, which include controlling global warming to within a 1.5 °C temperature rise, to mitigate the extreme ...
Duomin Wang, Yubin Huangfu, Zuoji Dong, Yiqi Dong   +3 more
semanticscholar   +1 more source

Advancing genomics research in Ireland: Part Two. Irish Health Research Forum report and recommendations [PDF]

, 2021
This report presents the proceedings of the Irish Health Research Forum on 12th May 2021. This is the second report to focus on advancing genetics and genomics in Ireland, and makes key recommendations for health research policy and practice in ...
Health Research Charities Ireland
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source