Results 71 to 80 of about 1,087,779 (267)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

奥林匹克公园瞭望塔

open access: yes, 2008
Overall view; At 258 metres (846 ft) in height it is the second tallest tower in the city after the Central Radio & TV Tower, and the fourth-tallest structure in the city.
China Architecture Design & Research Group
core  

SUSTAINABILITY CONCEPT OF BALI AGA ARCHITECTURE

open access: yes, 2013
Architecture is one of human works that consumed a lot of energy. Present research shows  that architecture consumed more than 50% of total energy in the world.
Siwalatri, Ni Ketut Ayu; Architecture Department Udayana University Denpasar Bali
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Nurbsters, Foldsters and Neoplasmatic Architecture

open access: yes, 2010
Presented on February 20, 2012 from 6:00 pm-8:00 pm in the Reinsch-Pierce Family Auditorium on the Georgia Tech campus.Marcos Cruz is the Director of the Bartlett School of Architecture in London where he is also Studio Master of MArch Unit 20.
Cruz, Marcos
core  

Buildings: Architecture Biennale 2023

open access: yes, 2023
Bianca Felicori (Université Catholique de Louvain) is part of the Public Program of the Italian pavilion as guest curator. Her lecture will take place on 9 June 2022 at Teatrino Palazzo Grassi, in Venice.
Felicori, Bianca   +1 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

An Architecture Story: Engaging Design Through Storytelling [PDF]

open access: yes, 2015
There are many historic pieces of architecture that are centuries old, but still somehow maintain the same level of magnificence and delight as they had when they were first completed.
Shek, Chuen Ho Howard
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

THE ROLE OF DATA ARCHITECTURE AS A PART OF ENTERPRISE ARCHITECTURE [PDF]

open access: yes
In the early days of computing, technology simply automated manual processes with greater efficiency. The new organizational context provides input into the data architecture and is the primary tool for the management and sharing of enterprise data.
Assoc. Prof. Anca Mehedintu Ph. D   +2 more
core  

Home - About - Disclaimer - Privacy