Results 81 to 90 of about 131,206,127 (300)

The coming-of-age of software architecture research [PDF]

Proceedings of the 23rd International Conference on Software Engineering. ICSE 2001, 2005
Over the past decade, software architecture research has emerged as the principled study of the overall structure of software systems, especially the relations among subsystems and components. From its roots in qualitative descriptions of useful system organizations, software architecture has matured to encompass broad explorations of notations, tools,
openaire   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cod, construction, and communities: Relations between fish and architectural history in Ísafjörður, Iceland [version 3; peer review: 1 approved, 3 approved with reservations, 1 not approved]

Open Research Europe
Understanding the interplay between ecological processes and human-built environments is key to addressing the entangled dynamics of marine and terrestrial landscapes, yet these relationships are often studied separately.
André Tavares, Ana Azevedo, Karl Benediktsson, Garðar Eyjólfsson, Rafael Sousa Santos, Michelle Valliant   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Serious Games in Architecture

, 2008
Presented on October 30, 2008 from 11:00 am to 12:00 noon in the Georgia Tech Architecture Library.Runtime: 48:15 minutesDr. Anatoliusz (Tolek) Lesniewski, Director, Interactive Media Architecture Group in Education (IMAGINE) Lab presented his research ...
Lesniewski, A. (Anatoliusz), Williams, Racel, Swarts, Matthew E.   +2 more
core   +1 more source

Aprender de la educación en arquitectura

Dearq, 2011
El autor plantea una serie de preguntas fundamentales alrededor de la investigación sobre educación en arquitectura, o la ausencia de ella. Después de una introducción, desglosa las preguntas: ¿por qué investigar sobre educación en arquitectura?
Necdet Teymur
doaj  

Ultrastructural Study of Microphysiological Systems of the Tumor Microenvironment

Small Science
The importance of studying the ultrastructure is underwritten by decades of research. Ultrastructural features help to understand pathological processes or inform disease diagnosis.
Paula Guerrero‐López, Karinna Georgiana Pele, Mariano Barrado, Pilar Alamán‐Díez, José Manuel García‐Aznar, Elena García‐Gareta   +5 more
doaj   +1 more source

Quantifying the Impact of Urban Growth on Urban Surface Heat Islands in the Bangkok Metropolitan Region, Thailand

Atmosphere
The urban built environment, comprising structures, roads, and various facilities, plays a key role in the formation of urban heat islands, which inflict considerable damage upon human society.
Pawinee Iamtrakul, Apinya Padon, Sararad Chayphong   +2 more
doaj   +1 more source