Results 151 to 160 of about 11,395,926 (309)

Towards information literacy indicators [PDF]

, 2008
From summary: This paper provides a conceptual framework for the identification of indicators of information literacy (IL) and proposes a pathway for cost effective and timely development.
Jesus Lau, Ralph Catts, Lau, Jesus, Catts, Ralph   +3 more
core  

Going paperless: the strengths and limitations of electronic research ethics information management system in a health training institution in Tanzania

BMC Health Services Research
Background Over the years, the processing of research proposals for ethical approvals have been done manually through a review of hard copies. Longer turn-around-time, increased financial costs to researchers and cumbersome submission processes are few ...
Rebecca D. Mkumbwa, Godwin Pancras, Nathanael S. Sirili   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Information security strategy in telemedicine and e-health systems: A case study of England’s shared electronic health record system

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 9/11/2010.Shared electronic health record (EHR) systems constitute an important Telemedicine and e-Health application. Successful implementation of shared
Mohammad, Yara Mahmoud
core  

Social media activism in Maldives; Information practices and civil society [PDF]

, 2017
Introduction. The study was designed to explore the information practices of a group of human rights activists in a campaign seeking to pressure the police service and government into investigating the disappearance of a journalist in the context of ...
Yerbury, H, Shahid, A
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Accessing grey literature in an integrated environment of scientific research information

, 2007
The DARE programme was initiated in the Netherlands by the SURF Foundation, the Dutch universities, the Royal Netherlands Academy of Arts and Sciences (KNAW), and the Netherlands Organisation for Scientific Research (NWO).
Meel, Marga van (KNAW Research Information), GreyNet, Grey Literature Network Service, Dijk, Elly (KNAW Research Information), Baars, Chris (KNAW Research Information), Hogenaar, Arjan (KNAW Research Information)   +4 more
core  

A review of Web information seeking research: considerations of method and foci of interest

Information Research: An International Electronic Journal, 2005
Introduction. This review shows that Web information seeking research suffers from inconsistencies in method and a lack of homogeneity in research foci. Background.
Konstantina Martzoukou
doaj  

Researchers' participation in and motivations for engaging with research information management systems. [PDF]

PLoS One, 2018
Stvilia B, Wu S, Lee DJ.
europepmc   +1 more source