Results 31 to 40 of about 2,590,478 (309)

Can urban metabolism models advance green infrastructure planning? Insights from ecosystem services research [PDF]

, 2018
Urban metabolism studies have gained momentum in recent years as a means to assess the environmental performance of cities and to point to more resource-efficient strategies for urban development.
Perrotti, Daniela, Stemke, Sven
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Boosting Vaccine Research: The 16-Year Journey of TRANSVAC Vaccine Infrastructure

Vaccines
TRANSVAC represents a long-running effort to accelerate the development of novel vaccines by integrating institutions from across Europe under a single collaborative framework.
William Martin, Catarina Luís, Stefan Jungbluth, Monika Slezak, Frank A. W. Verreck, Holger Spiegel, Carlos A. Guzman, António Roldão, Manuel J. T. Carrondo, Peter Van der Ley, Joaquim Segalés, Hazel M. Dockrell, Mei Mei Ho, Gabriel K. Pedersen, Maria Lawrenz, Ole F. Olesen   +15 more
doaj   +1 more source

Towards a generic research data management infrastructure [PDF]

, 2010
Until recent years, a focused and centralized strategy for the annotation, storage and curation of research data is something that has not been widely considered within academic communities.
Beard, Lorraine, Besson, Jon, Collins, Simon, Finch, June, Goff, Mhorag, Grahame, Tom, Halfpenny, Peter, McDerby, Mary, Poschen, Meik, Procter, Rob   +9 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Governing Personalized Health: A Scoping Review

Frontiers in Genetics, 2021
Genetic research is advancing rapidly. One important area for the application of the results from this work is personalized health. These are treatments and preventive interventions tailored to the genetic profile of specific groups or individuals.
Philipp Trein, Joël Wagner, Joël Wagner   +2 more
doaj   +1 more source

Polish grid infrastructure for science and research

, 2007
Structure, functionality, parameters and organization of the computing Grid in Poland is described, mainly from the perspective of high-energy particle physics community, currently its largest consumer and developer.
Gokieli, Ryszard, Nawrocki, Krzysztof, Padee, Adam, Stojda, Dorota, Wawrzyniak, Karol, Wislicki, Wojciech   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source