Results 51 to 60 of about 2,590,478 (309)
Enhancing Undergraduate Research Infrastructure [PDF]
2009 Annual Conference & Exposition Proceedings, 2020 Comment: 15 ...
Ali Ansari +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
e-Research Infrastructure and Community Research
The Journal of Community Informatics, 2011 Research is increasingly being conducted by multi-stakeholder teams which include the researchers themselves, funding authorities, industry collaborators and community stakeholders inside and outside universities, all of whom have dynamic requirements relating to research data, research artefacts and products, and published outcomes.
Tom Denison, Graeme Johanson
openaire +1 more source
Portfolio Infrastructure Investments: an Analysis of the European and UK Cases [PDF]
, 2015 Infrastructure has been receiving much attention in recent years. Investment banks and fund managers are increasingly promoting the investment characteristics of infrastructure assets and they argue that investing in infrastructure should be ideal for ...
Medda, F, Panayiotou, A
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The Impact of Research Data Infrastructures: The Case of the AlphaFold Database
CERN IdeaSquare Journal of Experimental InnovationWhile the scientific output of research infrastructures is well documented, the broader effects of their secondary outputs, such as computational resources and datasets, remain poorly understood.
Angelo Kenneth Romasanta +2 more
doaj +1 more source
Synthesis of qualitative research studies regarding the factors surrounding UK critical care trial infrastructure [PDF]
, 2019 © 2019 Author(s). Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJConducting clinical trials in critical care is integral to improving patient care.
Arulkumaran, Nishkantha +7 more
core +4 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source