Results 51 to 60 of about 873,999 (316)

A 'Research' Database on Infrastructure Economic Performance [PDF]

open access: yesSSRN Electronic Journal, 2005
info:eu-repo/semantics ...
Estache, Antonio, Goicoechea, A.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The relevance of standards for research infrastructures

open access: yes, 2006
Importance of standards as an essential aspect for any research infrastructure in the humanities. ISO Data category registry is designed within ISO TC37.
Francopoulo, Gil   +3 more
openaire   +5 more sources

The European Holocaust Research Infrastructure Portal [PDF]

open access: yesJournal on Computing and Cultural Heritage, 2017
Over the course of the past century, there have been significant changes in the practices of archives driven by the massive increase in the volume of records for archiving, a larger and more diverse user base, and the digital turn. This paper analyses work undertaken by the European Holocaust Research Infrastructure project (EHRI) to develop heritage ...
Tobias Blanke   +6 more
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Research Data Management in the Humanities: Challenges and Opportunities in the Canadian Context

open access: yesDigital Studies
In recent years, research funders across the world have implemented mandates for research data management (RDM) that introduce new obligations for researchers seeking funding.
Lisa Goddard   +2 more
doaj   +2 more sources

The Future of Digital Research Infrastructure

open access: yes, 2023
The presentation "The Future of Digital Research Infrastructure" was presented at the Base4NFDI User Conference 2025 (https://events.gwdg.de/event/1103/) as a keynote talk.
openaire   +2 more sources

Development of Bioinformatics Infrastructure for Genomics Research [PDF]

open access: yesGlobal Heart, 2017
Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure. H3ABioNet, a pan-African bioinformatics network, was established to build capacity specifically to enable H3Africa (Human Heredity and Health in Africa) researchers to
Mulder, Nicola J.   +45 more
openaire   +5 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

LOINC implementation approaches in academic medical research centers – results from a survey of CTSA sites

open access: yesJournal of Clinical and Translational Science
Reference standards are vital for harmonizing heterogeneous clinical data for research, but little is known about their implementations or costs. We surveyed NIH Clinical and Translational Science Awards (CTSA) hubs to assess operational dimensions of ...
Rachel L. Richesson   +3 more
doaj   +1 more source

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