Results 91 to 100 of about 4,098,242 (290)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

CIFAR10-DVS: An Event-Stream Dataset for Object Classification

open access: yesFrontiers in Neuroscience, 2017
Neuromorphic vision research requires high-quality and appropriately challenging event-stream datasets to support continuous improvement of algorithms and methods.
Hongmin Li   +5 more
doaj   +1 more source

Using the technology of the confessional as an analytical resource: four analytical stances towards research interviews in discourse analysis [PDF]

open access: yes, 2007
Among the various approaches that have developed from FOUCAULT's work is an Anglophone discourse analysis that has attempted to combine Foucaultian insights with the techniques of Conversation Analysis. An important current methodological issue in this
O'Rourke, B, Pitt, M
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Aerodynamics support of research instrument development [PDF]

open access: yes
A new velocimetry system is currently being developed at NASA LaRC. The device, known as a Doppler global velocimeter (DGV), can record three velocity components within a plane simultaneously and in near real time. To make measurements the DGV, like many
Miller, L. Scott
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Constructing One Component of a Survey Instrument to Measure the Influence of an Athletic Trainer\u27s Worldview in his Decision Making Process [PDF]

open access: yes, 2006
Athletic trainers are often put in situations where they may be pressured to make morally compromising decisions regarding issues ranging from insurance fraud to substance abuse.
Preusser, Daniel
core   +1 more source

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