Results 121 to 130 of about 24,456,135 (330)

Advanced high temperature instrument for hot section research applications [PDF]

Programs to develop research instrumentation for use in turbine engine hot sections are described. These programs were initiated to provide improved measurements capability as support for a multidisciplinary effort to establish technology leading to ...
Englund, D. R., Seasholtz, R. G.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Studying the Instrument Shelter [PDF]

, 2003
The purpose of this activity is to discover why an instrument shelter is built the way it is. Students construct shelters that have varying properties and place them in the same location or place similar shelters in different locations and compare ...
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core  

Salient Object Detection Guided Fish Phenotype Segmentation in High-Density Underwater Scenes via Multi-Task Learning

Fishes
Phenotyping technologies are essential for modern aquaculture, particularly for precise analysis of individual morphological traits. This study focuses on critical phenotype segmentation tasks for fish carcass and fins, which have significant ...
Jiapeng Zhang, Cheng Qian, Jincheng Xu, Xueying Tu, Xuyang Jiang, Shijing Liu   +5 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

AN ANALYSIS ON THE QUALITY OF ENGLISH TEXT BOOK THAT IS \ud USED AT THE FIRST YEAR OF JUNIOR HIGH SCHOOL OF SLTP 2 \ud RANDU AGUNG LUMAJANG BASED ON THE 2004 ENGLISH CURRICULUM [PDF]

, 2007
The success of teaching and learning process is absolutely based on the textbook used in the \ud classroom, however, it is quite difficult to find a suitable textbook for the students and teachers.
KUSUMA DEWI, DIAN
core  

Neuromorphic-enabled video-activated cell sorting

Nature Communications
Imaging flow cytometry allows image-activated cell sorting (IACS) with enhanced feature dimensions in cellular morphology, structure, and composition.
Weihua He, Junwen Zhu, Yongxiang Feng, Fei Liang, Kaichao You, Huichao Chai, Zhipeng Sui, Haiqing Hao, Guoqi Li, Jingjing Zhao, Lei Deng, Rong Zhao, Wenhui Wang   +12 more
doaj   +1 more source

Impact of Hot Air Drying on the Physicochemical Indicators, Astaxanthin Stability, and Degradation Kinetics of Antarctic Krill

Shipin gongye ke-ji
To investigate the effects of hot air drying on the physicochemical indicators, astaxanthin stability, and degradation kinetics of Antarctic krill, the study analyzed the changes in physicochemical indicators of Antarctic krill under different drying ...
Tiantian MA, Zhefei XIAO, Jie OUYANG, Jian SHEN, Xiaolin HOU   +4 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source