Results 51 to 60 of about 1,570,252 (311)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Criteria to assess the interdisciplinary research development: an issue formulation

Библиосфера, 2018
Scientometric studies have become an integral part of scientific libraries activities with introducing the state rating system in Russian science. Scientometric studies contribute to study long-term trends in the science development, help to discover ...
Yu. D. Prokof’Eva
doaj   +1 more source

Libraries and the management of research data [PDF]

, 2010
A discussion of the role of university libraries in the management of digital research data outputs. Reviews some of the recent history of progress in this area from a UK perspective, with reference to international ...
Lewis, M.J.
core  

Diversity Means Justice: Growing Grassroots Library Staff Diversity Leaders [PDF]

, 2015
Paper presented at the ACRL (Association of College & Research Libraries) 2015 Conference in Portland, Oregon.UT ...
Davis, Jee, Hogan, Kristen
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Data as a new research publication type: What could be the role of research libraries as service providers?

Liber Quarterly: The Journal of European Research Libraries
This article examines the evolving role of research libraries in supporting the recognition of datasets as legitimate academic outputs through data publishing. Although the academic community increasingly acknowledges the value of treating research data
Mari Elisa Kuusniemi, Susanna Nykyri
doaj   +1 more source

Global trends of libraries development: optimism vs pessimism (foreign literature review). Part 2

Библиосфера, 2019
The review examines modern library activity taking into account the influence of external technological and social environment, changes in scientific communications, education, modernization of data man­agement systems, etc.
N. S. Redkina
doaj   +1 more source

A Study of Legal Information Seeking Behaviour to Inform the Design of Electronic Legal Research Tools [PDF]

, 2006
Our work is motivated by the desire to support digital library users in ?getting to grips? with electronic resources. More specifically we are motivated by the desire to support users in understanding how to use, and in which situations it is appropriate
Blandford, A, Cox, AL, Makri, S
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Научная деятельность ГПНТБ СО РАН в цифрах (2007-2009 гг.)

Библиосфера, 2010
The impact of scientific activities of SPSL SB RAS during 2007-2009 are analyzed.

doaj