Results 101 to 110 of about 26,805,984 (378)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
On the methodology of management research [PDF]
Epistemology, methodology or philosophy of science, i.e., the foundations and validity of knowledge, have never been very popular subjects as applied to management research.
Rosanas, Josep M.
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Narrative Research Methodology in Mobile Work Research [PDF]
, 2011 This book review provides a summary of the content of the book Mobile Work, Mobile Lives: Cultural Accounts of Lived Experiences and a critical review of the methodological strengths of the articles included in the book.
Jin, Li
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Design Fiction Diegetic Prototyping: A Research Framework for Visualizing Service Innovations [PDF]
, 2019 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Purpose: This paper presents a design fiction diegetic prototyping methodology and research framework for ...
Belk, Russell +2 more
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Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
The role of philosophical context in the development of research methodology and theory [PDF]
, 2008 The research strategy dictates the major direction of the research and constitutes one of the important decisions made by the researcher. However, researchers’ understanding on theory at the outset of the research guides the design of the research.
Amaratunga, RDG +2 more
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Be(com)ing a reflexive researcher: a developmental approach to research methodology
, 2017 Our purpose in this article is to achieve a shift of focus away from a view of research methods as objectified procedures to be learnt by researchers, and towards the development of researchers who craft procedures integral to the environments in which ...
M. Attia, J. Edge
semanticscholar +1 more source
Qualitative and mixed methodology for online language teaching research [PDF]
, 2017 This paper provides an overview of CALL (Computer Assisted Language Learning), its history and current developments. It presents a rationale for moving CALL research forward, and outlines a particular approach to researching online language teaching and ...
Maja Mili\u10devi\u107, Tihana Kra\u161
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source