Results 121 to 130 of about 2,884,073 (259)

Impact of a Student-Led Research Methodology Course on Self-Perceived Research Competencies: A Quasi-experimental Study Among Medical Students in Panama, 2024. [PDF]

Cureus
Sáenz R, Cedeno-De Leon D, Palacios-Zimmermann P, Vega-Medina P, Rengifo A, Bucktron K, Noriega-Aguirre L.   +6 more
europepmc   +1 more source

Vignette Research Methodology: An Essential Tool for Quality Improvement Collaboratives. [PDF]

Healthcare (Basel), 2022
Payton KSE, Gould JB.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Tłı̨chǫ nàowoò hoghàseètǫǫ: learning a strong like two research methodology through the exploration of community-centered curation practices. [PDF]

AlterNative (Nga Pae Maramatanga (Organ))
Bourgeois RL.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Indigenous women's health and data sovereignty: imagining an Indigenous research methodology using quantitative methods. [PDF]

AlterNative (Nga Pae Maramatanga (Organ))
Crosschild C, Varcoe C, Brown HJ, Browne AJ.   +3 more
europepmc   +1 more source

Building a Low-Cost Wireless Biofeedback Solution: Applying Design Science Research Methodology. [PDF]

Sensors (Basel), 2023
Cheng CF, Lin CJ.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Smartphone-based activity research: methodology and key insights. [PDF]

Front Surg
Turlip RW, Chauhan D, Ahmad HS, Dagli MM, Hu BY, Chung RJ, Ghenbot Y, Gu BJ, Patel N, Kim RJ, Kincaid J, Verma A, Yoon JW.   +12 more
europepmc   +1 more source

The Art of Teaching Professional Practice: An Action Research Methodology Inspired by Ulrich's Systems Concepts. [PDF]

Syst Pract Action Res, 2023
van der Linde S, Goede R.
europepmc   +1 more source