Results 101 to 110 of about 25,687,414 (343)
Yarning: a responsive research methodology
, 2004 This paper explores 'yarning' as a research method which emerged in a cross-cultural PhD as a means of building a research partnership between feminist and Indigenous leaders in early childhood education. This method created an avenue for the researcher,
Power, Kerith
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A new application of contextualist methodology in case research
, 2006 Contextualist methodology is the main focus of discussion in this paper, and its attributes as a rigorous approach to case study methodology are discussed. In a departure from the usual practice of applying this methodology to processes of organisational
Chapman, Judith A.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A methodology for developing computational implementations of scientific theories [PDF]
, 2008 Computer programs have become a popular representation for scientific theories, particularly for implementing models or simulations of observed phenomena. Expressing a theory as an executable computer program provides many benefits, including: making all
Fernand Gobet +5 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Talanoa Research Methodology: A Developing Position on Pacific Research
, 2016 This paper contributes to the theorising on Pacific research approaches from a personal and Tongan perspective. At the same time, it suggests that the majority of the thinking and concepts discussed have similarities and common implications for most ...
T. Vaioleti
semanticscholar +1 more source
Constructivist research: methodology and practice
, 2005 Constructivist research and critical, postmodern and feminist methodology are related to each other. These methodologies use qualitative research methods extensively.
Fahy, Kathleen, Harrison, Karey
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Alchemy for inquiry: a methodology of applied phenomenology in educational research [PDF]
, 2015 This paper presents an original methodology, called Alchemy as Inquiry. It is a methodology grounded in pure phenomenology and made accessible for reflective research into one's own experiences.
Vallack, Jocene
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source