Results 51 to 60 of about 22,421,622 (338)

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Beriberi disease – a picture of thiamine deficiency in underdeveloped and highly developed countries

Journal of Education, Health and Sport, 2020
Introduction and purpose: Thiamin (Vitamin B1) is a water-soluble vitamin. It plays an important role in many biological processes, mainly in glucose metabolism. Its deficiency is called beriberi disease.
Agnieszka Blicharz, Magdalena Marzęda, Małgorzara Drozd, Jakub Czarnota, Halina Piecewicz-Szczęsna   +4 more
doaj   +1 more source

Topological genealogy: a methodology to research transnational digital governance in/through/as change [PDF]

, 2021
Mathias Decuypere, Steven Lewis
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The correlation between tuberculosis and diabetes incidence and the impact of mass migration on the development of tuberculosis and drug-resistant tuberculosis on the example of India and England

Journal of Education, Health and Sport, 2019
Introduction: Tuberculosis is still a major health concern around the world, especially in developing countries with very large populations. Diabetes may be responsible for the progression of Mycobacterium tuberculosis infection.
Dorota Sokół, Arkadiusz Standyło, Jakub Czarnota, Tomasz Skubel, Michał Dobrzyński, Halina Piecewicz-Szczęsna   +5 more
doaj   +3 more sources

Unclear etiology and current hypotheses of the pathogenesis of fibromyalgia

Journal of Education, Health and Sport, 2020
Introduction and purpose: Fibromyalgia is a chronic condition affecting almost 2% of the general population, mostly women. The main symptoms are chronic diffuse musculoskeletal pain or stiffness, tiredness,  nonrestorative sleep, anxiety, depression and ...
Małgorzata Drozd, Magdalena Marzęda, Agnieszka Blicharz, Jakub Czarnota, Halina Piecewicz-Szczęsna   +4 more
doaj   +1 more source

Neurological manifestations and complications of COVID-19. A literature review

Journal of Education, Health and Sport, 2021
Introduction. The first case of SARS-CoV-2 infection was identified in December 2019 in Wuhan, China. The disease spread rapidly worldwide and the WHO declared a pandemic on March 11, 2020. Although coronavirus disease 2019 (COVID-19) has been associated
Aleksandra Maria Krasa, Magdalena Kozioł, Halina Piecewicz-Szczęsna, Anna Łopuszyńska, Ewa Piekarska, Piotr Więsyk, Mateusz Pawlicki   +6 more
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Methodology for research II

Indian Journal of Anaesthesia, 2016
Research is a systematic process, which uses scientific methods to generate new knowledge that can be used to solve a query or improve on the existing system. Any research on human subjects is associated with varying degree of risk to the participating individual and it is important to safeguard the welfare and rights of the participants.
S Bala Bhaskar, M Manjuladevi
openaire   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source