Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Project Retrosight. Understanding the returns from cardiovascular and stroke research: Methodology Report [PDF]
, 2011 Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the ...
Buxton, MJ +4 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
PLoS Medicine, 2016 BackgroundDentists prescribe approximately 10% of antibiotics dispensed in UK community pharmacies. Despite clear clinical guidance, dentists often prescribe antibiotics inappropriately.
Paula Elouafkaoui +7 more
doaj +1 more source
Quality of Life Research and Methodology: Developing a Measure for Alaska Native Peoples [PDF]
, 2017 Quality of life (QOL) is often complicated by global measures that ignore the uniqueness of culture and context. The research is inundated with Western influence and colonized approaches, and indigenous ways of knowing are often overlooked and devalued ...
Crouch, Maria
core
Exploring the IT usage in SMEs from New Zealand, Columbia and Chile using action-research methodology [PDF]
, 2012 The theory on the adoption and use of information technology (IT) in small and medium enterprises (SMEs) is abundant. However, methodologically speaking, action-research (AR) has been little explored as a method of construction of this theory, despite ...
Cataldo, Alejandro +2 more
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Barriers to Early Breast Cancer Diagnosis in Sudanese Women Before the War
Breast Cancer: Targets and TherapyHana Eltayeb Salih Elamin,1 Hind Eltayeb Salih Elamin,2 Ghada Omer Hamad Abd El-Raheem,3 Mounkaila Noma1 1High Diploma in Research Methodology and Biostatistics, University of Medical Sciences and Technology UMST, Khartoum City, Khartoum State, Sudan ...
Elamin HES +3 more
doaj
Evaluation of interventions for informed consent for randomised controlled trials (ELICIT) : protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey [PDF]
, 2015 Acknowledgements This work was supported by personal fellowship award (to KG) from the Medical Research Council’s Strategic Skills Methodology programme.
Campbell, Marion K +5 more
core +2 more sources