Results 71 to 80 of about 25,687,414 (343)

Hepatotoxicity of anabolic androgenic steroids in sport

open access: yesJournal of Education, Health and Sport, 2020
Introduction and purpose: Anabolic-androgenic steroids (AAS) abuse is a common practice among professional as well as recreational athletes. The prevalence of this phenomenon seems to be continuously escalating, too.
Michał Jakub Sekuła   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Beriberi disease – a picture of thiamine deficiency in underdeveloped and highly developed countries

open access: yesJournal of Education, Health and Sport, 2020
Introduction and purpose: Thiamin (Vitamin B1) is a water-soluble vitamin. It plays an important role in many biological processes, mainly in glucose metabolism. Its deficiency is called beriberi disease.
Agnieszka Blicharz   +4 more
doaj   +1 more source

Methodology for research I

open access: yesIndian Journal of Anaesthesia, 2016
The conduct of research requires a systematic approach involving diligent planning and its execution as planned. It comprises various essential predefined components such as aims, population, conduct/technique, outcome and statistical considerations. These need to be objective, reliable and in a repeatable format.
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Unclear etiology and current hypotheses of the pathogenesis of fibromyalgia

open access: yesJournal of Education, Health and Sport, 2020
Introduction and purpose: Fibromyalgia is a chronic condition affecting almost 2% of the general population, mostly women. The main symptoms are chronic diffuse musculoskeletal pain or stiffness, tiredness,  nonrestorative sleep, anxiety, depression and ...
Małgorzata Drozd   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Getting busy teachers to do a card sort: Using Q Methodology online to research teacher viewpoints

open access: yes, 2022
This case study describes a Q methodology study which captured and analyzed the viewpoints of 45 UK teachers online. The teachers might liken their participation in the study to a “card sort” activity: their relative placement of statement cards ...
Shearman, J.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Phenomenological Research Methodology

open access: yesScientific Research Journal, 2019
The phenomenological research methodology relates to several approaches that in turn, they are applied to single cases or to the deliberate samples that are carefully chosen.
Neville Greening
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy