Results 91 to 100 of about 20,403,332 (296)
, 2014 This paper begins with the assumption that there is no perfect study. Rather, the process of conducting language acquisition research involves numerous decisions, each of which is accompanied by a set of strengths and weaknesses and which must be ...
Gurzynski-Weiss, L, Plonsky, L
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Reflexiones sobre la metodología de investigación social
Miscelánea Comillas, 2015 Se realiza una reflexión sobre los métodos y técnicas de investigación cualitativos y cuantitativos centrándose en cuatro aspectos fundamentales: la necesidad de conocer y utilizar los distintos métodos de investigación social por parte de los ...
Carmen Meneses Falcón
doaj
Statistical methods for linguistic research: Foundational Ideas - Part II
, 2016 We provide an introductory review of Bayesian data analytical methods, with a focus on applications for linguistics, psychology, psycholinguistics, and cognitive science.
Nicenboim, Bruno, Vasishth, Shravan
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Application of Qualitative Methods in Health Research: An Overview [PDF]
, 2010 Qualitative research is type of formative research that includes specialized techniques for obtaining in-depth responses about what people think and how they feel.
Deshmukh, PR +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
BMJ OpenIntroduction Economic evaluations in healthcare can guide practice and inform policy. The objective of this paper is to present the protocol for a health economic evaluation comparing the cost-effectiveness of prophylactic treatment using pantoprazole 40
Bram Rochwerg +8 more
doaj +1 more source