Results 161 to 170 of about 87,581,544 (292)

Statistical methods in research

The Lancet, 1993
E R, Greenberg, T A, Stukel, J A, Baron, D H, Freeman   +3 more
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

[Research methods and technological advancements in herbal material science]. [PDF]

Se Pu
Liu YF, Zhou H, Wang JX, Shen AJ, Liu D, Han Y, Yu WY, Yuan B, Wang Z, Zeng J, Xue XY, Feng JT, Guo ZM, Liang XM.   +13 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

From knowledge to action: Participatory research methods to create an action plan for healthier communities. [PDF]

PLoS One
Purkey E, Bartels SA, Carter R, Chan-Nguyen S, Cole M, Davison CM, Ford M, Jackson L, Knox B, Watson A, Bayoumi I.   +10 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Lessons learned from youth-engaged research methods to conduct qualitative analysis with a transgender and gender-diverse youth advisory board. [PDF]

PLoS One
Pham AH, Webster Z, Bean MK, Mazzeo S, Ahrens K, Thomson M.   +5 more
europepmc   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Integrating Eye Tracking in Acoustic Research: Methods for Sound Localization, Event Detection, Multimodal Sensing, and Perceptual Analysis. [PDF]

Sensors (Basel)
Ciaburro G, Puyana-Romero V.
europepmc   +1 more source