Results 231 to 240 of about 20,403,332 (296)

Application of observational research methods to real-world studies for rare disease drugs: A scoping review protocol. [PDF]

PLoS One
Patel YP, Ghaddar L, Lin Y, Karim N, Chan K, Dupuis L, Tadrous M.   +6 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Social Media Marketing of Non-Evidence-Based Women's Health Interventions: Protocol for a Content Analysis Using Participatory Research Methods.

JMIR Res Protoc
Nickel B, Copp T, Gram E, Hersch J, Hudson C, McFadden K, Pickles K, Smith J, Taba M, Graham A, Freeman B, Mintzes B, Doust J, Cohen D, McCaffery K.   +14 more
europepmc   +1 more source

Selecting Research Methods to Address Clinical Questions. [PDF]

Mov Disord Clin Pract
Bruno V, Aquino C, Pringsheim T.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Core concepts in statistics and research methods. Part I: statistical inference. [PDF]

BJA Educ
Sidebotham D, Hewson D.
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Gender scores in epidemiological research: methods, advantages and implications. [PDF]

Lancet Reg Health Eur
Ballering AV, Olde Hartman TC, Rosmalen JGM.   +2 more
europepmc   +1 more source