Results 191 to 200 of about 1,666,160 (306)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Maternal health research outputs and gaps in Latin America: reflections from the mapping study. [PDF]

Global Health, 2017
Vargas-Riaño E, Becerril-Montekio V, Becerra-Posada F, Tristán M.   +3 more
europepmc   +1 more source

DELTA (Difference ELicitation in TriAls)2 advice and recommendations for researchers and funder representatives – output from literature reviews, Delphi study, workshop and stakeholder engagement

, 2019
Jean Cook, Steven A. Julious, William Sones, L Hampson, Catherine Hewitt, JA Berlin, Deborah Ashby, Richard Emsley, DA Fergusson, Stephen J. Walters, Ecf Wilson, GS Maclennan, Nigel Stallard, John C. Rothwell, Martin Bland, Lindsay Brown, Craig Ramsay, Andrew Cook, David Armstrong, Daniel Altman, Luke Vale   +20 more
openalex   +1 more source

Comparative Evaluation of Research Output: AIIMS Vs PGIMER

, 2012
Harjinder Kaur
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Pattern analysis of award of Grant-in-Aid for Scientific Research with Research Outputs

, 2006
M. Nishizawa, Masamitsu NEGISHI, Morio Shibayama, Yuan SUN, Hiroyasu Nomura, Yoshitaka Mitsuda, Masashi MAEDA   +6 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Have we increased our efforts to identify strategies which encourage colorectal cancer screening in primary care patients? A review of research outputs over time. [PDF]

Prev Med Rep, 2018
Dodd N, Mansfield E, Carey M, Oldmeadow C, Sanson-Fisher R.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A numerical assessment of research outputs on South African estuaries

South African Journal of Science, 2013
Alan K. Whitfield, Ndiviwe G. Baliwe
doaj   +1 more source