Results 181 to 190 of about 5,285,257 (310)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A trainee-informed model for undergraduate neuroscience research programs serving marginalized students. [PDF]

Nat Neurosci
Cazares C, Patiño M, Contreras M, Gorman JC, Burgado J, Ali SA, van Engen Q, Kosik EL, Riviere P, Baltz ET, Agba CK, Preston M, Nagarajan A, Cressy J, Paredes N, Santiago C, White KL.   +16 more
europepmc   +1 more source

Biomedical Research Programs at Present and Future High-Energy Particle Accelerators. [PDF]

Front Phys, 2020
Patera V, Prezado Y, Azaiez F, Battistoni G, Bettoni D, Brandenburg S, Bugay A, Cuttone G, Dauvergne D, de France G, Graeff C, Haberer T, Inaniwa T, Incerti S, Nasonova E, Navin A, Pullia M, Rossi S, Vandevoorde C, Durante M.   +19 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Promoting resilience of large international collaborative research programs in times of global crisis. [PDF]

Ecol Evol, 2020
Trogisch S, Albert G, Du J, Wang Y, Xue K, Bruelheide H.   +5 more
europepmc   +1 more source

Research Programs in Japan [PDF]

Japanese Journal of Clinical Oncology, 1998
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A review of undergraduate research programs aimed at underrepresented students. [PDF]

STAR Protoc
Beasley HK, Vue Z, McReynolds MR, Neikirk K, Garza-Lopez E, Mungai M, Marshall AG, Shao B, Benjamin J, Wanjalla CN, Williams CR, Murray SA, Shuler HD, Kirabo A, Hinton A.   +14 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The Landscape of US and Global Rare Tumor Research Programs: A Systematic Review. [PDF]

Oncologist
Vivelo C, Reilly KM, Widemann BC, Wedekind MF, Painter C, O'Neill AF, Mueller S, Elemento O, Gross AM, Sandler AB.   +9 more
europepmc   +1 more source