Results 101 to 110 of about 6,302,219 (264)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fertility trends by social status [PDF]
This article discusses how fertility relates to social status with the use of a new dataset, several times larger than the ones used so far. The status-fertility relation is investigated over several centuries, across world regions and by the type of ...
Vegard Skirbekk
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Drilling Parameters Optimization Technology Status and Development Trend
Shiyou jixie, 2016 With the increasing complex conditions for offshore and underground exploitation,and the continuous development of drilling technology,tools,equipment and instrumentation technology,the corresponding monitoring while drilling technology and computer ...
Sha Linxiu
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Connotation, research status, and development directions of clean coal geology in China
Meitian dizhi yu kantan[Objective] The exploration and assessment of low-carbon, zero-emission, and maximized utilization of coal resources, emerge as a focus of coal geology in the 21st century.
Yuegang TANG +6 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Promet (Zagreb)Traffic accidents are one of the main causes of fatalities and serious injuries among both adults and children worldwide. Due to the ongoing significant socio-economic losses brought on by traffic accidents, precise estimation of the risk of accidents is
Mesut ULU, Yusuf Sait TÜRKAN
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Community participation agreements: a model for welfare reform from community-based research [PDF]
, 2001 Summary In its June 2001 budget, the Federal Government announced a new framework for welfare reform, Australians Working Together. One component of the framework is the proposed development of Community Participation Agreements in remote Indigenous ...
Diane Smith, Smith, Diane E
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