Results 121 to 130 of about 62,404,405 (312)

Biomarkers and Alzheimer’s disease: a bibliometric analysis

open access: yesFrontiers in Aging Neuroscience
ObjectiveThe diagnosis and treatment of biomarkers in Alzheimer’s disease has emerged as a prominent topic within Alzheimer’s disease research. In this paper, we conducted a bibliometric analysis of data from a wide range of literature in this field to ...
Linyi Yang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]

open access: yes
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Status of tokamak research [PDF]

open access: yes, 1979
An overall review of the tokamak program is given with particular emphasis upon developments over the past five years in the theoretical and experimental elements of the program. A summary of the key operating parameters for the principal tokamaks throughout the world is given.
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Brief to the Ontario Status of Women Council and the Attorney-General

open access: yes
The Ontario Committee on the Status of Women, a grassroots feminist group, was established in 1970. Its purpose was to seek implementation in Ontario of the Recommendations of the Royal Commission on the Status of ...
Ontario Committee on the Status of Women
core  

Medical Research Charities Group: Annual report 2018 [PDF]

open access: yes, 2019
2018 was a year of high activity and much progress for the MRCG. Fourteen exciting research projects were funded through our Joint Funding Scheme with the HRB, two impactful Irish Health Research Forum events were held and we did much to support our ...
Medical Research Charities Group
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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