Results 121 to 130 of about 901,210 (313)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Grantsmanship [PDF]

open access: yes, 2012
Lecture presentations hosted by the College of Nursing featuring faculty, graduate students, nursing professionals, and allied health experts. Each lunchtime lecture is devoted to a timely topic examining the training, research and scholarly needs of the
Pepper, Ginette
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research on the Application of Topic Models Based on Geological Disaster Information Mining

open access: yesInformation
Geological disasters, as a common occurrence, have a serious impact on social development in terms of their frequency of occurrence, disaster effects, and resulting losses.
Gang Cheng   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Imagination, mereotopology, and topic expansion [PDF]

open access: yes
Funding: The research and writing of this paper was supported by Cotnoir’s UKRI Frontier Research Grant, Instruments of Unity, Project Number 10004484. Aybuke Ozgun’s contribution received support from the project ‘The Logic of Conceivability’, funded by
Cotnoir, A. J., Özgün , Aybüke
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Decision-focussed resource modelling for design decision support [PDF]

open access: yes, 2009
Resource management including resource allocation, levelling, configuration and monitoring has been recognised as critical to design decision making. It has received increasing research interests in recent years. Different definitions, models and systems
Whitfield, R.I.   +10 more
core  

Environmental monitoring and analysis in support of Antrim oil shale research. Topical report, March 1978-February 1979

open access: yes, 1979
A program to assess environmental impacts of in situ Antrim oil shale processing experiments was carried out. This report covers the second year of an expected four year program. Activities included: monitoring of surface elevations for possible subsidence; monitoring for soil contamination from brines; monitoring surface and subsurface water quality ...
F. J. Tanis, G. S. Thomas
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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