Results 161 to 170 of about 3,368,371 (356)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

A educação infantil: reflexões a partir do tema do financiamento e conveniamento em periódicos nacionais

open access: yesEccoS – Revista Científica, 2012
In this work we present notes on the financing agreements and arrangements and Brazilian concerning the early childhood education in national journals. This paper comes from a study funded by São Paulo Research Foundation (FAPESP) which had as its main ...
Liliane R. Mello, Regiane H. Bertagna
doaj  

The aerobraking space transfer vehicle [PDF]

open access: yes
With the advent of the Space Station and the proposed Geosynchronous Operation Support Center (GeoShack) in the early 21st century, the need for a cost effective, reusable orbital transport vehicle has arisen.
Andrews, Glen   +9 more
core   +1 more source

Testbeds Support for Reproducible Research

open access: yesReproducibility@SIGCOMM, 2017
L. Nussbaum
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Undergraduate Research

open access: yesJournal of Rawalpindi Medical College, 2019
For people in medical field research is a continuous non ending process. Conducting research is an important component of post graduate training throughout the World. Recently more and more emphasis is being given to start research at undergraduate level.
Madeeha Nazar
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Firm migration patterns in in the Netherlands and in the United Kingdom. An end of twenty calm years of geographical interest [PDF]

open access: yes
Firm migration in the Netherlands and the United Kingdom Cees-Jan Pen and Ilaria Mariotti In the 1970s firm migration was an important research topic in West European economic geography.
Ilaria Mariotti
core  

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