Results 151 to 160 of about 2,048,409 (259)

Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study. [PDF]

Front Neurol, 2022
Liu YY, Yao RQ, Long LY, Liu YX, Tao BY, Liu HY, Liu JL, Li Z, Chen L, Yao YM.   +9 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The Significance of Probiotics in Aquaculture: A Review of Research Trend and Latest Scientific Findings. [PDF]

Antibiotics (Basel)
Mohammed EAH, Ahmed AEM, Kovács B, Pál K.   +3 more
europepmc   +1 more source

Worldwide productivity and research trend of publications concerning electroactive materials and spinal cord injury: A bibliometric study. [PDF]

Front Bioeng Biotechnol, 2023
Liu S, Song L, Dai W, Liu M, Zhang H, Zhang X, Li H, Liu X, Lv Y, Hu Y.   +9 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Global research trend of Herpes simplex keratitis: a bibliometric analysis and visualization from 1941 to 2024. [PDF]

Front Med (Lausanne)
Song K, Li S, Liu J, Kang Z.
europepmc   +1 more source

Issues in sustainable supply chain's futuristic technologies: a bibliometric and research trend analysis. [PDF]

Environ Sci Pollut Res Int, 2022
Wangsa ID, Vanany I, Siswanto N.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Large language models in orthopedics: An exploratory research trend analysis and machine learning classification. [PDF]

J Orthop
Velasquez Garcia A, Minami M, Mejia-Rodríguez M, Ortíz-Morales JR, Radice F.   +4 more
europepmc   +1 more source

Integrating the digital twin concept into the evaluation of reconfigurable manufacturing systems (RMS): literature review and research trend. [PDF]

Int J Adv Manuf Technol, 2023
Touckia JK.
europepmc   +1 more source