Results 101 to 110 of about 66,430,318 (252)

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

HRCI’s 2022 position paper – using data for better health research [PDF]

open access: yes, 2022
Our 2022 Position Paper is all about data and its importance to health research. The themes contained within are a priority for our member charities and have also been guided by the outcomes of the Irish Health Research Forum events, which HRCI runs. The
Health Research Charities Ireland, /
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Partial Indexation, Trend Inflation, and the Hybrid Phillips Curve [PDF]

open access: yes
This paper proposes a full description of the Calvo price-setting model based on partial prices indexation and studies the interaction between partial indexation and trend inflation.
Sahuc, J-G.
core  

Future Research and Trends in Ultra-Wideband Indoor Tag Localization

open access: yesIEEE Access
Ultra-wideband (UWB) signals are widely used for indoor tag localization because of their high accuracy, wide bandwidth, and low power consumption. The diversity and breadth of research in the field of UWB-indoor tag localization can be confusing for new
Gita Indah Hapsari   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

IFLA Trend Report 2021 Update

open access: yes, 2022
Will we see the importance of virtual services and spaces reinforced, or will there be an analogue backlash? Will we see further political polarisation and undermining of expertise, or will information literacy finally be recognised and valued?
International Federation of Library Associations and Institutions (IFLA)
core   +1 more source

A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots

open access: yesFrontiers in Medicine
BackgroundOptic atrophy (OA) is primarily caused by damage to the retinal pathway system, including widespread degeneration of retinal ganglion cells and axons, leading to visual impairment and blindness.
Liyuan Wang   +14 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Renewal through health research: HRCI position paper 2021

open access: yes, 2021
On January 28th we launched our 2021 position paper: Renewal through health research. It lays out a series of critical health research actions to help create a post-Covid Ireland where healthcare is world-class and based on evidence. It calls for:
Health Research Charities Ireland, /
core  

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