Results 121 to 130 of about 69,816,536 (306)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Comparing Different Explanations of the Volatility Trend [PDF]
We analyze the puzzling behavior of the volatility of individual stock returns over the past few decades. The literature has provided many different explanations to the trend in volatility and this paper tests the viability of the different explanations.
Amir Rubin, Daniel Smith
core
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Comments on Research trends of macrophage polarization: a bibliometric analysis
Yuh-Shan Ho, Yuan-Yuan Ji
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Analisis Bibliometrik Perkembangan Penelitian Preservasi Naskah Kuno di Perpustakaan
Preserving manuscripts is crucial to maintaining a nation's cultural heritage and historical knowledge. Manuscript collections have a high risk of damage, and preservation is the primary responsibility of various parties, including libraries.
Clarissa Prameswari +3 more
doaj +1 more source
The impact of Covid-19 on health research charities
HRCI conducted a survey of its members in December 2020 to ascertain the impact of Covid-19 on Irish Health Research Charities.
Health Research Charities Ireland, /
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Measuring trend output: how useful are the Great Ratios? [PDF]
Standard macroeconomic models suggest that the 'great ratios' of consumption to output and investment to output should be stationary. The joint behaviour of consumption, investment and output can then be used to measure trend output.
Cliff L.F. Attfield +1 more
core

