Results 121 to 130 of about 1,970,373 (243)

Dynamic Visualization of Computer-Aided Peptide Design for Cancer Therapeutics

Drug Design, Development and Therapy
Dan Hou,1– 3,* Haobin Zhou,1,2,* Yuting Tang,1,2 Ziyuan Liu,1,2 Lin Su,1,2 Junkai Guo,1,2 Janak Lal Pathak,1,2 Lihong Wu1,2 1Department of Basic Oral Medicine, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral ...
Hou D, Zhou H, Tang Y, Liu Z, Su L, Guo J, Pathak JL, Wu L   +7 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Triangulating the link between depression and liver disease: An integrative analysis of genetic, observational, and research trend data. [PDF]

Compr Psychoneuroendocrinol
Feng Z, Wang Y, Lu Q, Jin X, Qin Y, Jiang Y, Chen X, Li K.   +7 more
europepmc   +1 more source

Correction: Data Analysis of Physician Competence Research Trend: Social Network Analysis and Topic Modeling Approach. [PDF]

JMIR Med Inform, 2023
Yune SJ, Kim Y, Lee JW.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Comment on "Global research trend of graphene application in breast cancer: a bibliometric analysis". [PDF]

Int J Surg
Liu Y, Yang H, Peng J, Zhao Y.
europepmc   +1 more source

The global landscape and research trend of phase separation in cancer: a bibliometric analysis and visualization. [PDF]

Front Oncol, 2023
Li M, Zhang Y, Zhao J, Wang D.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Research trend on quantum dots for tumor diagnosis and therapy: a bibliometric analysis. [PDF]

Int J Surg
Feng Y, Wang D, Wang Z, Kang H.
europepmc   +1 more source

Bibliometric-Based Evaluation of the Neuromarketing Research Trend: 2010-2021. [PDF]

Front Psychol, 2022
Zhu Z, Jin Y, Su Y, Jia K, Lin CL, Liu X.   +5 more
europepmc   +1 more source