Results 81 to 90 of about 66,430,318 (252)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Trend Estimation [PDF]

open access: yes
Trend estimation deals with the characterization of the underlying, or long–run, evolution of a time series. Despite being a very pervasive theme in time series analysis since its inception, it still raises a lot of controversies.
Proietti, Tommaso
core  

Global trends in tertiary lymphoid structures: a bibliometric analysis from 2014 to 2023

open access: yesFrontiers in Immunology
Aim and backgroundTertiary lymphoid structures (TLS) are increasingly recognized for their role in immunity. Despite growing interest, a systematic bibliometric analysis of TLS-related research has been lacking.
Yiwen Bao   +14 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Optimal monetary policy under low trend inflation [PDF]

open access: yes
In the monetary policy literature it is commonly assumed that trend inflation is zero, despite overwhelming evidence that zero inflation is neither empirically relevant nor a practical objective for central bank policy.
Tiziano Ropele, Guido Ascari
core  

Global Trends in Battery Research and Development: The Contribution of the Center for Advanced Battery Collaboration

open access: yesElectrochemistry
The Center for Advanced Battery Collaboration (ABC) was established at the National Institute for Materials Science with the support of COI-NEXT, Japan Science and Technology Agency (JST).
Kei NISHIKAWA   +11 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Spurious regression under broken trend stationarity [PDF]

open access: yes
We study the phenomenon of spurious regression between two random variables when the generating mechanism for individual series follows a stationary process around a trend with (possibly) multiple breaks in its level and slope.
Daniel Ventosa-Santaularia   +1 more
core  

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