Results 191 to 200 of about 726,944 (258)

Arthroscopic Bursal Acromial Reconstruction With a Porcine Extracellular Matrix Graft

open access: yesArthroscopy Techniques, EarlyView.
Abstract Reinsertion of superior or posterosuperior rotator cuff ruptures in the elderly is often not possible. Patients can be left with symptoms of pain, loss of strength, and active range of motion. Bursal acromial reconstruction is an anchorless operative treatment method for painful, irreparable superior or posterosuperior rotator cuff ruptures in
Anton Ulstrup, Charlotte Stenqvist
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

open access: yesBiotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga   +2 more
wiley   +1 more source

A positive resection margin does not determine long-term survival following colorectal liver metastasis resection. [PDF]

open access: yesAnn Hepatobiliary Pancreat Surg
Konstantinou A   +5 more
europepmc   +1 more source

Lymph node mapping-based optimal bowel-resection margin and central radicality in colon cancer surgery: an international, prospective, observational cohort study. [PDF]

open access: yesESMO Gastrointest Oncol
Ueno H   +37 more
europepmc   +1 more source

Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy

open access: yesBMEMat, EarlyView.
The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu   +12 more
wiley   +1 more source

Predictors and risk model for positive circumferential resection margin after robot-assisted total mesorectal excision: retrospective cohort study. [PDF]

open access: yesBJS Open
Geitenbeek RTJ   +14 more
europepmc   +1 more source

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