Results 211 to 220 of about 726,944 (258)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Indocyanine green fluorescence imaging: Assessment of perfusion at pancreatic resection margin during pancreatoduodenectomy: A cross sectional study. [PDF]

Health Sci Rep
Ghimire R, Limbu Y, Regmee S, Maharjan DK, Mishra A, Pahari R, Thapa PB.   +6 more
europepmc   +1 more source

Fine‐Needle Aspiration of Salivary Gland Tumors With Low‐Grade Oncocytic Features: Focusing on Oncocytoma Versus Oncocytic Mucoepidermoid Carcinoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Salivary gland fine‐needle aspirates (FNAs) with low‐grade oncocytic features are diagnostically challenging due to the substantial morphologic overlap between benign oncocytic tumors and their malignant mimickers. This study evaluates the diagnostic discriminators, performance, and risk of malignancy of these lesions using the ...
Lois Araneta, Ying‐Ju Kuo, Jen‐Fan Hang   +2 more
wiley   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath, Azfar Neyaz, Samer Khader   +2 more
wiley   +1 more source

Development of a Predictive Nomogram for Circumferential Resection Margin in Rectal Cancer Surgery. [PDF]

J Surg Res
Shroder M, Ford MM, Ye F, Zhao Z, Khan A, McChesney S, Hopkins MB, Hawkins AT.   +7 more
europepmc   +1 more source

Changing Clinical Meaning of Resection Margin Status According to the Treatment Paradigm and the Potential Role of Perioperative Radiotherapy for Patients with Pancreatic Ductal Adenocarcinoma: An Updated Multicenter Retrospective Cohort Study. [PDF]

Ann Surg Oncol
Yun WG, Kwon W, Sohn HJ, Han Y, Chae YS, Jung HS, Cho YJ, Lim CS, Yoon YS, Jang JY.   +9 more
europepmc   +1 more source

Occipital irregular delta activity in focal epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei, Miklós Emri, Johanna Dömötör, Béla Clemens   +3 more
wiley   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

Assessment of the bony resection margin distance in bone-invasive oral cancer using laser-induced breakdown spectroscopy. [PDF]

Clin Oral Investig
Winnand P, Ooms M, Heitzer M, Vohl N, Lammert M, Hölzle F, Boernsen KO, Modabber A.   +7 more
europepmc   +1 more source

Impact of resection margin width on local recurrence following breast-conserving surgery and whole breast radiotherapy for pure ductal carcinoma in situ: a systematic review and meta-analysis. [PDF]

BMJ Oncol
Ezzat A, Shanthakumar D, Laskar N, Cutress RI, Hadjiminas D, Boland M, Joshi M, Patel R, Grant Y, Naik R, Bakri NAC, Hajev S, Elghazaly H, Holt J, Roddan A, Cleator S, Darzi A, Ashrafian H, Leff DR.   +18 more
europepmc   +1 more source