Results 91 to 100 of about 170,641 (296)

An axiomatization of family resemblance

open access: yesJournal of Applied Logic, 2007
AbstractWe invoke concepts from the theory of hypergraphs to give a measure of the closeness of family resemblance, and to make precise the idea of a composite likeness. It is shown that for any positive integer m, for any general term possessing any extent of family resemblance strictly greater than m, there is a taxonomical representation of the term
Ray E. Jennings, Dorian X. Nicholson
openaire   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Desmoplastic melanoma presenting as pyogenic granuloma: Report of a case with review of literature

open access: yesIndian Journal of Dermatology, 2010
An elderly female patient was referred to the author for the treatment of a large recurrent pyogenic granuloma in the sole of right foot for a period of 2 years. She underwent excisional surgeries at an outside facility twice in the past.
Ratnam B
doaj  

The Metaphysics of Sparse Properties and Deep Resemblance Nominalism

open access: yesProblemos
This paper introduces Deep Resemblance Nominalism (DRN) as a novel approach within the framework of resemblance nominalism and compares it to other forms of nominalism, including Rodriguez-Pereyra’s Resemblance Nominalism (RN).
Sun Demirli
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Édifier ses amis : enseignement et amicitia dans le livre I des Épîtres d’Horace

open access: yesCahiers des Études Anciennes
Book I of Horace’s Epistles appears to be the work of a mature poet, now committed to the pursuit of moral good, and is punctuated with advice, exhortations and messages of edification, delivered in the supple, uncluttered language of the sermo.
Robin Glinatsis
doaj  

Paternal Care May Influence Perceptions of Paternal Resemblance

open access: yesEvolutionary Psychology, 2010
Father-child resemblance is increasingly attracting attention from researchers interested in studying paternal investment. The current study sought to determine whether a quasi-experimental infant massage intervention would increase father's perceptions ...
Anthony A. Volk   +2 more
doaj   +1 more source

Resemblance and camouflage in Graeco-Roman antiquity

open access: yesSign Systems Studies, 2010
In the twenty-eighth book of the Naturalis Historia Pliny the Elder claims that, if a chameleon’s left leg is roasted together with a herb bearing the same name, and everything is mixed with ointment, cut in lozenges, and stored in a wooden little box ...
Massimo Leone
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

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