Results 71 to 80 of about 546,202 (245)
Que signifie « se ressembler » en biologie?
Biology works on particular subjects. Because of its historicity, each biological entity is unique. Yet we need to bring them together to be able to talk about them in a general way.
Guillaume Lecointre, Philippe Huneman
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Parental Investment and Resemblance: Replications, Refinements, and Revisions
Evolutionary theory predicts that men should be more concerned with issues of false paternity than women should be concerned with false maternity. In an earlier study ( Volk and Quinsey, 2002 ), we studied how infant cues of resemblance influenced adults'
Anthony A. Volk, Vernon L. Quinsey
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Father-child facial resemblance is an important cue for men to evaluate paternity. Previous studies found that fathers’ perceptions of low facial resemblance with offspring lead to low confidence of paternity.
Yu eQuanlei +5 more
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Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Self-duality in quantum impurity problems
We establish the existence of an exact non-perturbative self-duality in a variety of quantum impurity problems, including the Luttinger liquid or quantum wire with impurity.
A. Schmid +13 more
core +1 more source
O presente trabalho visa a uma análise comparativa das noções de "esfera", de Bakhtin (1992, 1999), e de "espaço discursivo", de Pêcheux (1997), com o intuito de elucidar o tratamento conferido à espacialidade pelos mencionados autores.
Renata Silva
doaj

