Results 11 to 20 of about 845,239 (199)

Emerging opportunities and challenges for the future of reservoir computing

Nature Communications
Reservoir computing originates in the early 2000s, the core idea being to utilize dynamical systems as reservoirs (nonlinear generalizations of standard bases) to adaptively learn spatiotemporal features and hidden patterns in complex time series.
Min Yan, Can Huang, Peter Bienstman, Peter Tino, Wei Lin, Jie Sun   +5 more
semanticscholar   +1 more source

A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses

Nature, 2019
A stable latent reservoir for HIV-1 in resting CD4+ T cells is the principal barrier to a cure1–3. Curative strategies that target the reservoir are being tested4,5 and require accurate, scalable reservoir assays.
Katherine M. Bruner, Z. Wang, F. Simonetti, A. Bender, K. J. Kwon, Srona Sengupta, E. Fray, Subul A. Beg, A. Antar, K. Jenike, Lynn N. Bertagnolli, A. Capoferri, J. Kufera, Andrew E Timmons, Christopher L. Nobles, J. Gregg, N. Wada, Y. Ho, Hao Zhang, J. Margolick, J. Blankson, S. Deeks, F. Bushman, J. Siliciano, G. Laird, R. Siliciano   +25 more
semanticscholar   +1 more source

Viral zoonotic risk is homogenous among taxonomic orders of mammalian and avian reservoir hosts

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Identifying whether novel human viruses disproportionately originate from certain animal groups could inform risk-based allocations of research and surveillance effort. Whether such “special reservoirs” exist remains controversial.
Nardus Mollentze, D. Streicker
semanticscholar   +1 more source

An Introduction to Reservoir Simulation Using MATLAB/GNU Octave

, 2019
This book provides a self-contained introduction to the simulation of flow and transport in porous media, written by a developer of numerical methods. The reader will learn how to implement reservoir simulation models and computational algorithms in a ...
Knut-Andreas Lie
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Greenhouse Gas Emissions from Reservoir Water Surfaces: A New Global Synthesis.

BioScience, 2016
Collectively, reservoirs created by dams are thought to be an important source of greenhouse gases (GHGs) to the atmosphere. So far, efforts to quantify, model, and manage these emissions have been limited by data availability and inconsistencies in ...
B. Deemer, J. Harrison, Siyue Li, Jake J. Beaulieu, T. DelSontro, N. Barros, José F. Bezerra-Neto, Stephen M. Powers, Marco A. dos Santos, J. Arie Vonk   +9 more
semanticscholar   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

The lung is a site of platelet biogenesis and a reservoir for hematopoietic progenitors

Nature, 2017
Platelets are critical for haemostasis, thrombosis, and inflammatory responses, but the events that lead to mature platelet production remain incompletely understood.
Emma Lefrançais, Guadalupe Ortiz-Muñoz, A. Caudrillier, B. Mallavia, Fengchun Liu, D. Sayah, E. Thornton, M. Headley, T. David, S. Coughlin, M. Krummel, A. Leavitt, E. Passegué, M. Looney   +13 more
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Reservoir computing using dynamic memristors for temporal information processing

Nature Communications, 2017
Reservoir computing systems utilize dynamic reservoirs having short-term memory to project features from the temporal inputs into a high-dimensional feature space.
Chao Du, F. Cai, Mohammed Affan Zidan, Wen Ma, Seung Hwan Lee, W. Lu   +5 more
semanticscholar   +1 more source