Results 151 to 160 of about 257,548 (365)
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Focal Spot, Fall/Winter 1989 [PDF]
, 1989 https://digitalcommons.wustl.edu/focal_spot_archives/1053/thumbnail ...
core +1 more source
A Plug‐and‐Play Volume Minimizing Micromixer
Advanced Science, EarlyView.ABSTRACT Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio‐analysis and point‐of‐care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates ...
Kirill Kolesnik +3 more
wiley +1 more source
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Exploring and practicing “integrated residency and fellowship teaching rounds” in neurology
Neike lilun yu shijianThe standardized fellowship and the standardized residency training are important components of China's post-graduation medical education system. According to the national guidelines for standardized fellowship, it is necessary to establish a structured ...
Xiaodong YANG +5 more
doaj +1 more source
Recent Residency Program Graduate Pledges Ongoing Support [PDF]
, 2013 After graduating from Jefferson’s surgical residency program in 2008, Negar Golesorkhi, MD, went on to complete a prestigious breast surgical oncology fellowship at Allegheny Medical Center.
core +1 more source
Consensus Formation and Change are Enhanced by Neutrality
Advanced Science, EarlyView.Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag +3 more
wiley +1 more source
Focal Spot, Fall/Winter 1992 [PDF]
, 1992 https://digitalcommons.wustl.edu/focal_spot_archives/1062/thumbnail ...
core +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Leadership considerations for executive vice chairs, new chairs, and chairs in the 21st century. [PDF]
, 2013 The need to fulfill academic goals in the context of significant economic challenges, new regulatory requirements, and ever-changing expectations for leadership requires continuous adaptation.
Kunkel, Elisabeth J.S. +3 more
core +1 more source