This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song +9 more
wiley +1 more source
Prioritizing Electrocardiogram Interpretation for Emergency Medicine Residency Training: A Modified Delphi Study. [PDF]
Yee J +4 more
europepmc +1 more source
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao +10 more
wiley +1 more source
Development and evaluation of a case-based learning program integrated with the BOPPPS model in neurosurgical residency training: a prospective controlled educational study. [PDF]
Shen J +7 more
europepmc +1 more source
An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni +6 more
wiley +1 more source
Decline in maternal mortality in Guyana observed after development and implementation of obstetrics and gynecology residency training program. [PDF]
Quimper M +12 more
europepmc +1 more source
Low N/P cells enable controllable lithium plating, allowing the lithium plating degree (DLi) to be quantified and linked to thermal safety. Pressure signals during calibration provide a non‐destructive route to diagnose DLi, while thermal response tests define safety levels and management strategies. The framework remains applicable in commercial 12 Ah
Haonan Liu +10 more
wiley +1 more source
Application research of "Script Killing" immersive teaching method based on cross-experimental design during emergency department residency training rotations. [PDF]
Zhang D +8 more
europepmc +1 more source
Ru‐doping‐induced defect engineering enables freestanding Ru–MoO3‐x flexible films with enriched oxygen vacancies, modulated band structure, and enhanced charge transport. The optimized electrode delivers ultrahigh capacitance approaching the theoretical limit of MoO3, while assembled asymmetric supercapacitors exhibit high energy density, wide‐voltage
Xiaoqing Bin +8 more
wiley +1 more source
Integrating iHEC into standardized residency training for chronic disease management: a structural equation analysis of competency outcomes via digital health platforms. [PDF]
Xie D +5 more
europepmc +1 more source

