Results 41 to 50 of about 9,537 (255)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dynamic Scene 3D Reconstruction of an Uncooperative Resident Space Object
AIAA SCITECH 2026 ForumCharacterization of uncooperative Resident Space Objects (RSO) play a crucial role in On-Orbit Servicing (OOS) and Active Debris Removal (ADR) missions to assess the geometry and motion properties. To address the challenges of reconstructing tumbling uncooperative targets, this study evaluates the performance of existing state-of-the-art 3D ...
Bala Prenith Reddy Gopu +7 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Uncertainty Quantification for Space Situational Awareness and Traffic Management
Sensors, 2019 This paper presents a sensor-orientated approach to on-orbit position uncertainty generation and quantification for both ground-based and space-based surveillance applications.
Samuel Hilton +5 more
doaj +1 more source
The Astrophysical Journal, 2023 Studying a centi-parsec supermassive black hole binary (SMBHB) would allow us to explore a new parameter space in active galactic nuclei, and these objects are also potential sources of gravitational waves.
Wu Jiang +8 more
doaj +1 more source
Instance Segmentation for Feature Recognition on Noncooperative Resident Space Objects
Journal of Spacecraft and Rockets, 2022 Active debris removal and unmanned on-orbit servicing missions have gained interest in the last few years, along with the possibility to perform them through the use of an autonomous chasing spacecraft. In this work, new resources are proposed to aid the implementation of guidance, navigation, and control algorithms for satellites devoted to the ...
Niccolò Faraco +2 more
openaire +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
AerospaceIn the last few years, many space surveillance initiatives have started to consider the problem represented by resident space object overpopulation. In particular, the European Space Surveillance and Tracking (EUSST) consortium is in charge of providing ...
Marco Felice Montaruli +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conjunction Analysis Software Suite for Space Surveillance and Tracking
AerospaceThe increasing number of objects in Earth orbit has encouraged the development of space surveillance and tracking (SST) applications. A critical aspect of SST is the identification and characterization of close encounters between pairs of space objects ...
Sergio Bonaccorsi +6 more
doaj +1 more source