Results 41 to 50 of about 5,464,510 (283)

Effects of Landscape Features on Bird Community in Winter Urban Parks

open access: yesAnimals, 2022
Urban parks, as critical components of the urban green space, have practical significance in studying the influence of landscape characteristics on birds. Nine urban parks in Fuzhou, China, were used as study objects to explore the influence of landscape
Peilin Huang   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Optimal Tasking of Ground-Based Sensors for Space Situational Awareness Using Deep Reinforcement Learning

open access: yesSensors, 2022
Space situational awareness (SSA) is becoming increasingly challenging with the proliferation of resident space objects (RSOs), ranging from CubeSats to mega-constellations.
Peng Mun Siew, Richard Linares
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Overview of High-Power and Wideband Radar Technology Development at MIT Lincoln Laboratory

open access: yesRemote Sensing
This paper summarizes over 60 years of radar system development at MIT Lincoln Laboratory, from early research on satellite tracking and planetary radar to the present ability to perform the centimeter-resolution imaging of resident space objects and ...
Michael MacDonald   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Characterisation of resident space objects using multistatic interferometric inverse synthetic aperture radar imaging

open access: yesIET Radar, Sonar & Navigation
This paper illustrates an interferometric inverse synthetic aperture radar based on three‐dimensional imaging and rotational velocity estimation from a multistatic setup with three ground‐based radars with non‐orthogonal baselines.
Manjunath Thindlu Rudrappa   +2 more
doaj   +1 more source

Space Situational Awareness in Very Low Earth Orbit for Re-Entry Object Monitoring

open access: yesAerospace
As the number of objects in orbit increases every year, the number of objects re-entering Earth’s atmosphere grows as well. Re-entry path prediction is tricky, as atmospheric modeling lacks accuracy and requires constant monitoring of the object during ...
Ruth Huang   +4 more
doaj   +1 more source

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