Results 51 to 60 of about 10,148 (283)

Dynamic Scene 3D Reconstruction of an Uncooperative Resident Space Object

AIAA SCITECH 2026 Forum
Characterization of uncooperative Resident Space Objects (RSO) play a crucial role in On-Orbit Servicing (OOS) and Active Debris Removal (ADR) missions to assess the geometry and motion properties. To address the challenges of reconstructing tumbling uncooperative targets, this study evaluates the performance of existing state-of-the-art 3D ...
Bala Prenith Reddy Gopu, Timothy Jacob Huber, George Nehma, Patrick Quinn, Madhur Tiwari, Matt Ueckermann, David Hinckley, Christopher McKenna   +7 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Conjunction Analysis Software Suite for Space Surveillance and Tracking

Aerospace
The increasing number of objects in Earth orbit has encouraged the development of space surveillance and tracking (SST) applications. A critical aspect of SST is the identification and characterization of close encounters between pairs of space objects ...
Sergio Bonaccorsi, Marco Felice Montaruli, Pierluigi Di Lizia, Moreno Peroni, Alessandro Panico, Marco Rigamonti, Francesco Del Prete   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

RESIDENT SPACE OBJECT IDENTIFICATION IN ARBITRARY UNRESOLVED SPACE IMAGES

, 2023
Identifying resident space objects (RSOs) in arbitrary space imagery with little a-priori information is a challenging, yet crucial next step in space-domain awareness applications.
Anderson, Joseph, Anderson, Annika, Zuehlke, David, Lovell, Thomas Alan, Canales Garcia, David   +4 more
core  

Prediction and Image Formation for Serendipitous Resident Space Object Underflights of Landsat 8

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Non-Earth imaging (NEI) of resident space objects (RSO) has become more readily available recently due to an expanding commercial sector focusing specifically on the NEI task, as well as high spatial resolution Earth imaging systems being agile enough to
Michael G. Gartley
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Resident Space Object (RSO) Tracking in Space-Based, Low Resolution, Non-Constant-Attitude Imagery

Remote Sensing
Resident Space Objects (RSOs) are a collection of both man-made and natural objects in near-Earth space. Given their large orbital velocities and rapidly increasing quantity, they pose a collision threat to space assets, necessitating better Space ...
Perushan Kunalakantha, Vithurshan Suthakar, Paul Harrison, Matthew Driedger, Randa Qashoa, Gabriel Chianelli, Regina S. K. Lee   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source