Results 71 to 80 of about 10,148 (283)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Advanced Sensor Tasking Strategies for Space Object Cataloging

Aerospace
Space Surveillance and Tracking (SST) plays a crucial role in ensuring space safety. To this end, accurate and numerous observational resources are needed to build and maintain a catalog of space objects. In particular, it is essential to develop optimal
Alessandro Mignocchi, Sebastian Samuele Rizzuto, Alessia De Riz, Marco Felice Montaruli   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

SHAPE MODELING, ATTITUDE ESTIMATION, AND CLASSIFICATION OF ARTIFICIAL RESIDENT SPACE OBJECTS (RSO) USING PHOTOMETRIC LIGHT CURVES

, 2021
Light curve inversion (LCI) has proven valuable in using photometric measurements to optimize various physical parameters of a resident space object (RSO) such as rotational period about its own spin axis, pole orientation and others.
Balachandran, Katiyayni
core  

Orbit Determination of Resident Space Objects with the Multibeam Radar Sensor BIRALES [PDF]

, 2018
Near-Earth space has become progressively more crowded in active satellites, inactive spacecraft and debris. Consequently, an international effort is currently being devoted to improving the performance of the network of optical and radar sensors for ...
Naldi, Giovanni, Marco Schiaffino, Bianchi, Germano, Germano Bianchi, Claudio Portelli, Pupillo, Giuseppe, Denis Cutajar, Mauro Roma, Portelli, Claudio, Roma, Mauro, Claudio Bortolotti, Giovanni Naldi, Federico Perini, Walter Villadei, Bortolotti, Claudio, Pierluigi Di Lizia, Massari, Mauro, Mattana, Andrea, Cutajar, Denis, Reali, Marco, Di Lizia, Pierluigi, Magro, Alessio, Villadei, Walter, Matteo Losacco, Alessio Magro, Andrea Mattana, Perini, Federico, Mauro Massari, Schiaffino, Marco, Marco Reali, Losacco, Matteo, Giuseppe Pupillo   +31 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

The Resident Space Object Detection Method Based on the Connection between the Fourier Domain Image of the Video Data Difference Frame and the Orbital Velocity Projection

Journal of Astronomy and Space Sciences
A method for resident space object detection in video stream processing using a set of matched filters has been proposed. Matched filters are constructed based on the connection between the Fourier spectrum shape of the difference frame and the ...
Vasilina Baranova, Alexander Spiridonov, Dmitrii Ushakov, Vladimir Saetchnikov   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source